New hope for advanced colorectal cancer: targeted drug M9140 enters early trial

NCT ID NCT06806046

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 33 times

Summary

This early-phase study tests an experimental drug called M9140 in 12 Chinese adults with advanced colorectal cancer that has not responded to standard treatments. The drug is designed to deliver chemotherapy directly to cancer cells that carry a specific marker (CEACAM5). The main goals are to check safety and see if the drug can shrink tumors.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, China

  • The Sixth Affiliated Hospital of Sun Yat-sen University

    Guangzhou, China

Conditions

Explore the condition pages connected to this study.