Virus-Based therapy targets deadly brain cancers in early trial

NCT ID NCT02062827

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 28 times

Summary

This early-stage study tests the safety of a lab-modified herpes virus (M032) that delivers an immune-boosting protein (IL-12) directly into aggressive brain tumors. The trial includes 29 adults with recurrent glioblastoma or similar cancers who have already tried standard treatments. The goal is to find the safest dose and see if the virus can help control the disease.

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Contacts and locations

Locations

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

Conditions

Explore the condition pages connected to this study.