Which antibiotic works best for m. xenopi lung infection?
NCT ID NCT01298336
First seen Nov 19, 2025 · Last updated Jun 23, 2026 · Updated 35 times
Summary
This study tested two different antibiotic combinations to treat a rare lung infection caused by M. xenopi bacteria. 92 adults received either clarithromycin or moxifloxacin along with two other antibiotics. The main goal was to see which combination cleared the bacteria from sputum after 6 months of treatment.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Assistance Publique Hôpitaux de Marseille
Marseille, 13009, France
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Assistance Publique Hôpitaux de Paris CHU Avicenne
Bobigny, 93009, France
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Assistance Publique Hôpitaux de Paris Hôpital BICHAT
Paris, 75018, France
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Assistance Publique Hôpitaux de Paris Hôpital Bicetre
Le Kremlin-Bicêtre, 94275, France
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Assistance Publique Hôpitaux de Paris Hôpital Saint Antoine
Paris, 75012, France
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Assistance Publique Hôpitaux de Paris Hôpital Saint Louis
Paris, 75010, France
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Assistance Publique Hôpitaux de Paris, hôpital TENON
Paris, 75020, France
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CH Abbeville
Abbeville, 80142, France
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CH Argenteuil
Argenteuil, 95100, France
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CH Béthune
Béthune, 62408, France
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CH Cannes
Cannes, 06401, France
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CH Compiègne
Compiègne, Compiègne, 60321, France
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CH Gonesse
Gonesse, 95503, France
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CH Intercommunal Meulan
Les Mureaux, Les Mureaux, 78250, France
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CH Le MANS
Le Mans, 72037, France
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CH Saint-Nazaire
Saint-Nazaire, Saint-Nazaire, 44606, France
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CH Sud Francilien
Corbeil-Essonnes, 91100, France
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CH Troyes
Troyes, Troyes, 10003, France
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CH de Roubaix
Roubaix, 59056, France
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CH de Saint Quentin
Saint-Quentin, 02100, France
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CH de Tourcoing
Tourcoing, 59208, France
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CH de Valenciennes
Valenciennes, 59300, France
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CHU Amiens
Amiens, 80054, France
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CHU Angers
Angers, 49033, France
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CHU Besançon
Besançon, 25030, France
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CHU Bordeaux Hôpital Haut Leveque
Pessac, 33604, France
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CHU Brest La Cavale
Brest, 29609, France
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CHU Caen
Caen, 14033, France
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CHU Clermont Ferrand Hôpital Gabriel Mont pied
Clermont-Ferrand, 63000, France
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CHU Dijon
Dijon, 21079, France
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CHU Grenoble
Grenoble, 38043, France
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CHU Lille Hôpital Calmette
Lille, 59037, France
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CHU Limoges Hôpital de Cluzeau
Limoges, 87042, France
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CHU Lyon Hôpital La Croix Rousse
Lyon, 69004, France
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CHU Montpellier Hôpital Arnaud de Villeneuve
Montpellier, 34295, France
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CHU Nancy
Vandœuvre-lès-Nancy, 54511, France
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CHU Nantes
Nantes, 44000, France
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CHU Nice
Nice, 06002, France
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CHU Poitiers
Poitiers, 86000, France
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CHU Reims
Reims, 51100, France
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CHU Rouen
Rouen, 76031, France
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CHU Toulouse
Toulouse, 31059, France
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CHU Tours Hôpital BRETONNEAU
Tours, 37044, France
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CHU de Rennes Hôpital Ponchaillou
Rennes, 35033, France
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CHU de Saint Etienne
Saint-Etienne, 42055, France
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CHU de Strasbourg
Strasbourg, 67091, France
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Centre Intercommunal de Créteil
Créteil, 94010, France
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Centre National de Reference Des Mycobactéries
Paris, PARIS, 75013, France
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Chr Orleans
Orléans, 45067, France
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Hopital René DUBOS
Pontoise, 95300, France
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Hopital Saint-Joseph
Marseille, 13008, France
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Hôpital FOCH
Suresnes, 92150, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
clarithromycin or moxifloxacin (antibiotics)
What this could lead to
If successful, this could help identify a more effective antibiotic combination for treating M. xenopi lung infections.
What could go wrong
This is a completed Phase 3 trial with only 92 participants, so results may not apply to all patients. Antibiotic resistance or side effects could limit effectiveness.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.