Which antibiotic wins against this tough lung bug?

NCT ID NCT01298336

Completed Disease control Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested two different antibiotics—clarithromycin or moxifloxacin—alongside standard drugs to treat a rare lung infection caused by M. xenopi bacteria. Researchers tracked whether patients' sputum samples became bacteria-free after 6 months. The goal was to find the more effective combination to control the infection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: clarithromycin or moxifloxacin (antibiotics)
What this could lead to: If successful, this could show which antibiotic combination works better to clear M. xenopi lung infections, improving treatment guidelines.
What could go wrong: This is a completed Phase 3 trial with only 92 participants, so results may not apply to all patients. Antibiotics can cause side effects like stomach upset or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

latent tuberculosis infection mycobacterial infectious disease Mycobacterium xenopi infection pulmonary tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATYPICAL; MYCOBACTERIUM, PULMONARY, TUBERCULOUS

Contacts and locations

Locations

Assistance Publique Hôpitaux de Marseille

Marseille, 13009, France
Assistance Publique Hôpitaux de Paris CHU Avicenne

Bobigny, 93009, France
Assistance Publique Hôpitaux de Paris Hôpital BICHAT

Paris, 75018, France
Assistance Publique Hôpitaux de Paris Hôpital Bicetre

Le Kremlin-Bicêtre, 94275, France
Assistance Publique Hôpitaux de Paris Hôpital Saint Antoine

Paris, 75012, France
Assistance Publique Hôpitaux de Paris Hôpital Saint Louis

Paris, 75010, France
Assistance Publique Hôpitaux de Paris, hôpital TENON

Paris, 75020, France
CH Abbeville

Abbeville, 80142, France
CH Argenteuil

Argenteuil, 95100, France
CH Béthune

Béthune, 62408, France
CH Cannes

Cannes, 06401, France
CH Compiègne

Compiègne, Compiègne, 60321, France
CH Gonesse

Gonesse, 95503, France
CH Intercommunal Meulan

Les Mureaux, Les Mureaux, 78250, France
CH Le MANS

Le Mans, 72037, France
CH Saint-Nazaire

Saint-Nazaire, Saint-Nazaire, 44606, France
CH Sud Francilien

Corbeil-Essonnes, 91100, France
CH Troyes

Troyes, Troyes, 10003, France
CH de Roubaix

Roubaix, 59056, France
CH de Saint Quentin

Saint-Quentin, 02100, France
CH de Tourcoing

Tourcoing, 59208, France
CH de Valenciennes

Valenciennes, 59300, France
CHU Amiens

Amiens, 80054, France
CHU Angers

Angers, 49033, France
CHU Besançon

Besançon, 25030, France
CHU Bordeaux Hôpital Haut Leveque

Pessac, 33604, France
CHU Brest La Cavale

Brest, 29609, France
CHU Caen

Caen, 14033, France
CHU Clermont Ferrand Hôpital Gabriel Mont pied

Clermont-Ferrand, 63000, France
CHU Dijon

Dijon, 21079, France
CHU Grenoble

Grenoble, 38043, France
CHU Lille Hôpital Calmette

Lille, 59037, France
CHU Limoges Hôpital de Cluzeau

Limoges, 87042, France
CHU Lyon Hôpital La Croix Rousse

Lyon, 69004, France
CHU Montpellier Hôpital Arnaud de Villeneuve

Montpellier, 34295, France
CHU Nancy

Vandœuvre-lès-Nancy, 54511, France
CHU Nantes

Nantes, 44000, France
CHU Nice

Nice, 06002, France
CHU Poitiers

Poitiers, 86000, France
CHU Reims

Reims, 51100, France
CHU Rouen

Rouen, 76031, France
CHU Toulouse

Toulouse, 31059, France
CHU Tours Hôpital BRETONNEAU

Tours, 37044, France
CHU de Rennes Hôpital Ponchaillou

Rennes, 35033, France
CHU de Saint Etienne

Saint-Etienne, 42055, France
CHU de Strasbourg

Strasbourg, 67091, France
Centre Intercommunal de Créteil

Créteil, 94010, France
Centre National de Reference Des Mycobactéries

Paris, PARIS, 75013, France
Chr Orleans

Orléans, 45067, France
Hopital René DUBOS

Pontoise, 95300, France
Hopital Saint-Joseph

Marseille, 13008, France
Hôpital FOCH

Suresnes, 92150, France