New Two-Drug attack on Tough-to-Treat blood cancer

NCT ID NCT02651662

Summary

This early-stage study is testing the safety and side effects of a combination of two new drugs, odronextamab and cemiplimab, in patients with aggressive B-cell lymphoma that has come back or hasn't responded to at least two prior treatments. The main goal is to find a safe dose for future testing. Researchers will also check if the drugs show any signs of helping to control the cancer.

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Contacts and locations

Locations

  • Cancer & Hematology Centers of Western Michigan

    Grand Rapids, Michigan, 49546, United States

  • Chaim Sheba Medical Center

    Ramat Gan, 5265601, Israel

  • Copernicus Memorial Hospital

    Lodz, 93-513, Poland

  • Dana Farber/Harvard Cancer Center - PO box 849168

    Boston, Massachusetts, 02215, United States

  • Hadassah Medical Center

    Jerusalem, 91200, Israel

  • Harvard Medical School - Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Hospital Clinic de Barcelona

    Barcelona, 08036, Spain

  • Hospital Clinico Universitario de Salamanca

    Salamanca, 37007, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Fundacion Jimenez Diaz

    Madrid, 28040, Spain

  • Hospital Universitario Marques de Valdecilla

    Santander, Cantabria, 39008.0, Spain

  • Hospital Universitario Puerta de Hierro - Majadahonda

    Majadahonda, Madrid, 28222, Spain

  • Hospital Universitario Quironsalud Madrid

    Pozuelo de Alarcón, Madrid, 28223, Spain

  • Hospital Universitario Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, 08041, Spain

  • Institut Catala dOncologia (ICO Hospitalet)

    Barcelona, 08908, Spain

  • Johns Hopkins University

    Baltimore, Maryland, 21205, United States

  • MD Anderson Cancer Center- Madrid

    Madrid, 28033, Spain

  • Medical University Vienna

    Vienna, 1190, Austria

  • Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy Warszawa

    Warsaw, 02781, Poland

  • Pratia MCM Krakow

    Krakow, Malopolska, 30-510, Poland

  • Pratia Onkologia Katowice

    Katowice, 40-519, Poland

  • Soroka

    Beersheba, 84101, Israel

  • Tel Aviv Sourasky Medical Center

    Tel Aviv, 64239, Israel

  • Uniklinikum Salzburg (LKH) Universitatsklinik fur Innere Medizin III

    Salzburg, 5020, Austria

  • Universitatsklinikum Jena

    Jena, 7747, Germany

  • Universitatsklinikum Schleswig-Holstein, Campus Kiel

    Kiel, 24105, Germany

  • University Hospital Frankfurt

    Frankfurt am Main, 60590, Germany

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • Uniwersyteckie Centrum Kliniczne

    Gdansk, Pomeranian Voivodeship, 80-952, Poland

Conditions

Explore the condition pages connected to this study.