500 lyme patients enrolled in Long-Term NIH observation study
NCT ID NCT00028080
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 29 times
Summary
This study follows 500 people with active Lyme disease to better understand the infection, its biological markers, and how the immune system responds. Participants receive standard FDA-approved treatments and undergo regular checkups, blood draws, and sometimes leukapheresis. No experimental treatments are offered. The goal is to build a research base for future advances in Lyme disease.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could improve understanding of Lyme disease and help identify biological markers for better diagnosis or treatment.
What could go wrong
This is an observational study, not a treatment trial. It will not directly test new therapies, and results may take years to translate into patient care.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.