New radiation therapy shows promise for Tough-to-Treat prostate cancer

NCT ID NCT06520345

First seen May 15, 2026 · Last updated May 15, 2026

Summary

This study tests whether adding a radioactive drug (lutetium-177 rosopatamab) to standard treatment helps men with a specific type of advanced prostate cancer that has stopped responding to hormone therapy. About 520 men with PSMA-positive metastatic castration-resistant prostate cancer will be randomly assigned to receive the drug plus standard care or standard care alone. The goal is to see if the combination slows cancer growth and improves survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    NOT_YET_RECRUITING

    Ankara, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ankara University Cebeci Hospital

    RECRUITING

    Ankara, Turkey (Türkiye)

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Auckland City Hospital

    RECRUITING

    Grafton, Auckland, 92024, New Zealand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Austin Health

    RECRUITING

    Heidelberg, 3084, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Australian Prostate Centre

    RECRUITING

    Melbourne, Victoria, 3051, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Biogenix Molecular LLC

    ACTIVE_NOT_RECRUITING

    Miami, Florida, 33165, United States

  • Chao Family Comprehensive Cancer Centre

    ACTIVE_NOT_RECRUITING

    Orange, California, 92868, United States

  • Columbia University Herbert Irving Comphrensive Cancer Center

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Genesis Care Windsor

    RECRUITING

    Windsor, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GenesisCare Maitland

    RECRUITING

    East Maitland, 2323, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • GenesisCare Murdoch

    RECRUITING

    Perth, Western Australia, 6150, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GenesisCare North Adelaide

    RECRUITING

    North Adelaide, 5006, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • GenesisCare Tugun

    RECRUITING

    Tugun, 4224, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • GensisCare Cabrini

    RECRUITING

    Malvern, 3144, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hacettepe University Medical Faculty

    RECRUITING

    Ankara, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • INITIO Medical Group

    RECRUITING

    Burnaby, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Intermountain Health

    ACTIVE_NOT_RECRUITING

    Murray, Utah, 84107, United States

  • Intermountain Health

    ACTIVE_NOT_RECRUITING

    Salt Lake City, Utah, 84112, United States

  • Maslak Acibadem Hospital

    NOT_YET_RECRUITING

    Istanbul, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mater Health Services Pty Ltd

    NOT_YET_RECRUITING

    Brisbane, 4101, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Nepean Hospital

    RECRUITING

    Sydney, New South Wales, 2747, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • New Zealand Clinical Research - Christchurch

    RECRUITING

    Christchurch, 8011, New Zealand

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • OHSU Knight Cancer Center

    ACTIVE_NOT_RECRUITING

    Portland, Oregon, 97239, United States

  • Royal North Shore Hospital

    RECRUITING

    Saint Leonards, 2065, Australia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sunnybrook Research Institute

    RECRUITING

    Toronto, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • United Theranostics

    ACTIVE_NOT_RECRUITING

    Glen Burnie, Maryland, 21061, United States

  • University College London Hospitals

    RECRUITING

    London, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Hospital

    ACTIVE_NOT_RECRUITING

    Cleveland, Ohio, 44106, United States

  • Westmead Hospital

    RECRUITING

    Sydney, New South Wales, 2143, Australia

    Contact

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wollongong Hospital

    RECRUITING

    Wollongong, New South Wales, 2500, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • XCancer Omaha

    ACTIVE_NOT_RECRUITING

    Omaha, Nebraska, 68130, United States

Conditions

Explore the condition pages connected to this study.