New radiation therapy aims to slow advanced prostate cancer
NCT ID NCT06520345
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 3 trial tests whether adding a targeted radiation drug (lutetium-177 rosopatamab) to standard care can help men with a specific type of advanced prostate cancer that has stopped responding to hormone therapy. The study will enroll 520 men across multiple countries. Participants are randomly assigned to receive either the radiation drug plus standard care or standard care alone. The main goal is to see if the combination delays cancer growth or death.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lutetium-177 rosopatamab tetraxetan (a targeted radiation drug)
What this could lead to
If successful, this could provide a new treatment option that slows cancer progression and extends survival for men with advanced prostate cancer that has stopped responding to hormone therapy.
What could go wrong
This is an early-stage Phase 3 trial, so results are not guaranteed. The radiation drug may cause side effects like fatigue, low blood counts, or kidney issues, and it may not work better than standard care alone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ankara Bilkent City Hospital
NOT_YET_RECRUITINGAnkara, Turkey (Türkiye)
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Ankara University Cebeci Hospital
RECRUITINGAnkara, Turkey (Türkiye)
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Auckland City Hospital
RECRUITINGGrafton, Auckland, 92024, New Zealand
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Austin Health
RECRUITINGHeidelberg, 3084, Australia
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Australian Prostate Centre
RECRUITINGMelbourne, Victoria, 3051, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Biogenix Molecular LLC
ACTIVE_NOT_RECRUITINGMiami, Florida, 33165, United States
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Chao Family Comprehensive Cancer Centre
ACTIVE_NOT_RECRUITINGOrange, California, 92868, United States
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Columbia University Herbert Irving Comphrensive Cancer Center
RECRUITINGNew York, New York, 10032, United States
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Genesis Care Windsor
RECRUITINGWindsor, United Kingdom
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GenesisCare Maitland
RECRUITINGEast Maitland, 2323, Australia
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GenesisCare Murdoch
RECRUITINGPerth, Western Australia, 6150, Australia
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GenesisCare North Adelaide
RECRUITINGNorth Adelaide, 5006, Australia
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GenesisCare Tugun
RECRUITINGTugun, 4224, Australia
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GensisCare Cabrini
RECRUITINGMalvern, 3144, Australia
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Hacettepe University Medical Faculty
RECRUITINGAnkara, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••
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INITIO Medical Group
RECRUITINGBurnaby, Canada
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Intermountain Health
ACTIVE_NOT_RECRUITINGMurray, Utah, 84107, United States
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Intermountain Health
ACTIVE_NOT_RECRUITINGSalt Lake City, Utah, 84112, United States
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Maslak Acibadem Hospital
NOT_YET_RECRUITINGIstanbul, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mater Health Services Pty Ltd
NOT_YET_RECRUITINGBrisbane, 4101, Australia
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Nepean Hospital
RECRUITINGSydney, New South Wales, 2747, Australia
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New Zealand Clinical Research - Christchurch
RECRUITINGChristchurch, 8011, New Zealand
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OHSU Knight Cancer Center
ACTIVE_NOT_RECRUITINGPortland, Oregon, 97239, United States
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Royal North Shore Hospital
RECRUITINGSaint Leonards, 2065, Australia
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Sunnybrook Research Institute
RECRUITINGToronto, Canada
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United Theranostics
ACTIVE_NOT_RECRUITINGGlen Burnie, Maryland, 21061, United States
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University College London Hospitals
RECRUITINGLondon, United Kingdom
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University Hospital
ACTIVE_NOT_RECRUITINGCleveland, Ohio, 44106, United States
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Westmead Hospital
RECRUITINGSydney, New South Wales, 2143, Australia
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Wollongong Hospital
RECRUITINGWollongong, New South Wales, 2500, Australia
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XCancer Omaha
ACTIVE_NOT_RECRUITINGOmaha, Nebraska, 68130, United States