Targeted drug combo tested to tame lupus flares
NCT ID NCT05306873
Summary
This study aimed to see if two different drug combinations could better control active systemic lupus erythematosus (SLE) in specific groups of patients. It tested mycophenolate mofetil (MMF) alone or combined with voclosporin in adults with moderate to severe, non-organ-threatening lupus. The trial was designed to match treatments to patients based on their immune system profiles, but it was terminated early after enrolling only 12 participants.
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Contacts and locations
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Locations
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Columbia University Medical Center: Department of Medicine, Division of Rheumatology
New York, New York, 10032, United States
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Emory University School of Medicine: Division of Rheumatology
Atlanta, Georgia, 30307, United States
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Feinstein Institute for Medical Research: Center for Autoimmune and Musculoskeletal Diseases
Manhasset, New York, 11030, United States
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Massachusetts General Hospital: Rheumatology, Allergy and Immunology, Center for Immunology and Inflammatory Diseases
Boston, Massachusetts, 02114, United States
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Oklahoma Medical Research Foundation: Arthritis and Clinical Immunology Research Program
Oklahoma City, Oklahoma, 73104, United States
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PennState Health Milton S. Hershey Medical Center: Division of Rheumatology
Hershey, Pennsylvania, 17033, United States
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Piedmont Healthcare: Rheumatology Atlanta
Atlanta, Georgia, 30318, United States
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UCLA Medical Center: Division of Rheumatology
Los Angeles, California, 90095, United States
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University of North Carolina at Chapel Hill; Thurston Arthritis Research Center: Division of Rheumatology, Allergy, and Immunology
Chapel Hill, North Carolina, 27599, United States
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Yale University School of Medicine: Rheumatology, Allergy & Immunology
New Haven, Connecticut, 06519, United States
Conditions
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