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Lupus skin drug trial halted early – only 8 volunteers joined

NCT ID NCT05879718

Terminated Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times

Summary

This study tested an experimental drug called PF-06823859 for adults with lupus that affects the skin. The goal was to see if the drug could reduce skin inflammation and improve symptoms. The trial was stopped early and only enrolled 8 people instead of the planned 48, so results are very limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cutaneous lupus erythematosus systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUPUS ERYTHEMATOSUS, CUTANEOUS LUPUS ERYTHEMATOSUS, SYSTEMIC

Contacts and locations

Locations

  • Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • DermEffects

    London, Ontario, N6H 5L5, Canada

  • Dermatological and Venereological Hospital Andreas Syggros

    Athens, 161 21, Greece

  • Dermatology Research Associates

    Los Angeles, California, 90045, United States

  • Dermatology on Bloor - Research Toronto

    Toronto, Ontario, M4W 2N4, Canada

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Virgen Del Rocio

    Seville, 41013, Spain

  • Ionos Dragoumi 5 Kaisariani

    Kaisarianí, Attikí, 16121, Greece

  • Mayo Clinic Hospital

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic in Arizona - Scottsdale

    Scottsdale, Arizona, 85259, United States

  • The Kirklin Clinic of UAB Hospital

    Birmingham, Alabama, 35233, United States

  • The University of Alabama at Birmingham

    Birmingham, Alabama, 35249, United States

  • The University of Kansas Hospital

    Kansas City, Kansas, 66160, United States

  • University General Hospital "ATTIKON" - General Hospital of West Attica "H AGIA VARVARA"

    Chaïdári, Attikí, 124 62, Greece

  • University of Alabama at Birmingham - School of Medicine

    Birmingham, Alabama, 35233, United States

  • University of Alabama at Birmingham, Department of Dermatology

    Birmingham, Alabama, 35233, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • Whitby Health Centre

    Whitby, Ontario, L1P 0p9, Canada

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