New injection could shrink nasal polyps and ease breathing

NCT ID NCT06454240

Completed Symptom relief Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 28 times

Summary

This study tested a new drug called lunsekimig in 79 adults with chronic sinusitis and nasal polyps that didn't get better with standard steroid sprays. Participants received either the drug or a placebo as a shot under the skin for 24 weeks. The main goal was to see if the drug could shrink polyps and improve nasal congestion.

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Contacts and locations

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Locations

Advanced Research Institute - Odgen- Site Number : 8400022

Ogden, Utah, 84405, United States
Alamo ENT Associates Site Number : 8400001

San Antonio, Texas, 78258, United States
Allergy & Rheumatology- Site Number : 8400005

La Jolla, California, 92037, United States
Berkson Medical - McKinney- Site Number : 8400014

McKinney, Texas, 75070, United States
Eastern Virginia Medical School (EVMS) Medical Group- Site Number : 8400008

Norfolk, Virginia, 23510, United States
Emory University Hospital Midtown- Site Number : 8400012

Atlanta, Georgia, 30308, United States
Essential Medical Research- Site Number : 8400020

Tulsa, Oklahoma, 74137, United States
Gary Gross Pharmaceutical Research & Consulting, Inc. Site Number : 8400004

Dallas, Texas, 75231, United States
Harvard Medical School - Brigham and Women's Hospital Site Number : 8400016

Boston, Massachusetts, 02115, United States
Investigational Site Number : 0320001

Buenos Aires, 1121, Argentina
Investigational Site Number : 0320002

Rosario, Santa Fe Province, 2000, Argentina
Investigational Site Number : 0320003

Mendoza, 5500, Argentina
Investigational Site Number : 0560001

Leuven, 3000, Belgium
Investigational Site Number : 0560002

Ghent, 9000, Belgium
Investigational Site Number : 1000001

Sofia, 1612, Bulgaria
Investigational Site Number : 6160001

Warsaw, Masovian Voivodeship, 00-909, Poland
Investigational Site Number : 6160002

Krakow, Lesser Poland Voivodeship, 31-033, Poland
Investigational Site Number : 6160003

Katowice, Silesian Voivodeship, 40-611, Poland
Investigational Site Number : 6160004

Poznan, 60-693, Poland
Investigational Site Number : 6160005

Warsaw, Masovian Voivodeship, 02-507, Poland
Investigational Site Number : 6160007

Wroclaw, 53-034, Poland
Investigational Site Number : 8260001

Newcastle upon Tyne, NE7 7DN, United Kingdom
Investigational Site Number : 8260003

Manchester, M13 9WL, United Kingdom
Investigational Site Number : 8260004

Gloucester, Gloucestershire, GL1 3NN, United Kingdom
James A Haley Veterans' Hospital- Site Number : 8400015

Tampa, Florida, 33612, United States
McGovern Medical School - UT Physicians Dermatology - Bellaire Station- Site Number : 8400017

Bellaire, Texas, 77401, United States
Sacramento Ear Nose & Throat - Roseville- Site Number : 8400003

Roseville, California, 95661, United States
Senta Clinic- Site Number : 8400025

San Diego, California, 92018, United States
The Allergy Group - Asthma & Allergy Boise- Site Number : 8400002

Boise, Idaho, 83706, United States

Conditions

Explore the condition pages connected to this study.

CHRONIC RHINOSINUSITIS WITH NASAL POLYPS