New Lung-Box device could save more transplant organs
NCT ID NCT02234128
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a device called the Toronto EVLP System that keeps donated lungs warm and breathing outside the body. The goal was to see if it is safe to extend the time doctors can preserve and check the lungs before transplant. 118 adults waiting for a lung transplant took part. Researchers compared their outcomes to standard transplant procedures, focusing on survival and lung function after 30 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Toronto EVLP System (device that keeps donor lungs warm and breathing outside the body)
What this could lead to
If successful, this could allow more donor lungs to be used for transplant by giving doctors more time to assess them safely.
What could go wrong
This is a safety study, not a test of cure. The device may not improve outcomes, and there are standard risks of lung transplant like organ rejection or infection.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Duke University Health System
Durham, North Carolina, 27705, United States
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Inova Fairfax Medical Campus
Falls Church, Virginia, 22042, United States
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Loyola University Medical Center
Chicago, Illinois, 60153, United States
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Mayo Clinic Jacksonville
Jacksonville, Florida, 32224, United States
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UPMC
Pittsburgh, Pennsylvania, 15213, United States
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University of Maryland Medical Center
Baltimore, Maryland, 21201, United States
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University of Michigan Health System
Ann Arbor, Michigan, 48109, United States