Breathing machine settings may boost chest therapy in ICU

NCT ID NCT06805357

Recruiting now Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how different ventilator modes affect lung volume changes during chest physiotherapy in 40 ICU patients on breathing machines. Researchers will compare two common ventilator settings to see which one helps the lungs expand more after chest compressions. The goal is to improve airway clearance and lung function in critically ill patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Chest physiotherapy by rib cage compressions
What this could lead to: If successful, this study could help doctors choose the best ventilator settings during chest physiotherapy to improve lung function in critically ill patients.
What could go wrong: This is a small, early-stage study with only 40 participants, so results may not apply to all ICU patients. It measures short-term lung volume changes, not long-term outcomes.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AIRWAY CLEARANCE CHEST PHYSIOTHERAPY INTENSIVE CARE INVASIVE MECHANICAL VENTILATION

Contacts and locations

Locations

Intensive Care Medicine Department Henri Mondor Hospital
RECRUITING

Créteil, 94000, France

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