New MRI scan could spot lung transplant rejection early

NCT ID NCT05550662

First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 20 times

Summary

This study tested a new type of MRI (called hyperpolarized 129Xe MRI) to see if it could detect early signs of lung rejection in people who had a double lung transplant. Researchers wanted to find out if this scan could show lung function and structure changes without needing a biopsy. The study planned to include 15 adults, but was stopped early after enrolling only 6 participants.

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Contacts and locations

Locations

  • Hospital for Sick Chilldren

    Toronto, Ontario, M5G 1X8, Canada

  • The Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada

Conditions

Explore the condition pages connected to this study.