Scientists probe lung microbiome to unlock TB secrets

NCT ID NCT04700579

Recruiting now Knowledge-focused Sponsor: University of Stellenbosch Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at the bacteria living in the lungs of people with active tuberculosis (TB) and how they change with treatment. Researchers will compare lung bacteria in diseased and healthy areas, and also check the mouth, nose, and gut. They aim to understand how these microbes influence the body's immune response and recovery. The goal is to find new ways to diagnose or treat TB by targeting the lung microbiome.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could point toward new ways to diagnose or treat TB by targeting the lung microbiome.
What could go wrong: This is an observational study, not a treatment trial. It may not lead directly to new therapies, and results may not apply to all TB patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HIV/AIDS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

AIDS latent tuberculosis infection pulmonary tuberculosis tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV/AIDS TB - TUBERCULOSIS

Contacts and locations

Locations

Kraaifontein Community Health Centre
RECRUITING

Cape Town, Western Cape, 7570, South Africa
Scottsdene Clinic
RECRUITING

Cape Town, Western Cape, 7570, South Africa
Wallacedene Clinic
RECRUITING

Cape Town, Western Cape, 7570, South Africa

More trials for these conditions

Other studies related to the condition(s) this trial covers.