Scientists peer inside lungs to see TB exposure effects

NCT ID NCT05027958

First seen Nov 06, 2025 · Last updated May 20, 2026 · Updated 28 times

Summary

This study looked at how immune cells in the lungs respond to a TB protein called PPD. Seventeen adults—some with latent TB and some without—received PPD directly into their lungs during a bronchoscopy. Researchers then collected lung cells and used scans to measure immune activity. The goal was to better understand local immune responses, not to treat or cure TB.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.