Blood test strategy could guide better lung cancer treatment

NCT ID NCT02856893

Summary

This study is testing the best way to use the drug osimertinib for advanced lung cancer with a specific genetic change (EGFR mutation). It compares starting osimertinib right away versus starting another drug first and switching to osimertinib later, guided by a blood test that looks for cancer DNA. The main goal is to see which approach keeps the cancer from growing for the longest time.

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Contacts and locations

Locations

  • Assistance Publique - Hopitaux de Marseille - Hopital Nord

    Marseille, France

  • CHU Toulouse - Hopital Larrey

    Toulouse, France

  • CHU de Brest

    Brest, France

  • Centre Francois Baclesse

    Caen, France

  • Centre Hopitalier Intercommunal De Creteil

    Créteil, France

  • Centre Paul Strauss

    Strasbourg, France

  • Gustave Roussy

    Villejuif, France

  • Hospital Clinic Universitari de Barcelona

    Barcelona, Spain

  • Hospital De La Santa Creu I Sant Pau

    Barcelona, Spain

  • Hospital Universitario 12 De Octubre

    Madrid, Spain

  • Hospital Universitario Ramon y Cajal

    Madrid, Spain

  • Institut Bergonie

    Bordeaux, France

  • Institut Catala d'Oncologia - ICO Badalona - Hospital De Mataro

    Mataró, Spain

  • Institut Jules Bordet

    Brussels, Bruxelles Région, 1070, Belgium

  • Institut Paoli-Calmettes

    Marseille, France

  • Institut de Cancerologie de Lorraine

    Vandœuvre-lès-Nancy, France

  • King Hussein Cancer Center

    Amman, Jordan

  • Medical University of Gdansk

    Gdansk, Poland

  • The Institute Of Oncology

    Ljubljana, Slovenia

  • University Clinic Golnik

    Golnik, Slovenia

  • University Hospital A Coruna-Hospital Teresa Herrera

    A Coruña, Spain

  • Vall d'Hebron Institut d'Oncologia

    Barcelona, Spain

  • Virgen del Rocio University Hospital

    Seville, Spain

Conditions

Explore the condition pages connected to this study.