New combo therapy tested to fight back when lung cancer returns

NCT ID NCT04765059

Summary

This study is for people with advanced non-small cell lung cancer whose cancer started growing again outside the brain after initial treatment with osimertinib. It tests whether continuing osimertinib while adding standard chemotherapy works better and controls the cancer longer than chemotherapy alone. About 98 participants will be randomly assigned to receive either the drug combination or chemotherapy with a placebo pill.

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Contacts and locations

Locations

  • Research Site

    Silver Spring, Maryland, 20910, United States

  • Research Site

    Boston, Massachusetts, 02114, United States

  • Research Site

    Beijing, 100005, China

  • Research Site

    Beijing, 100142, China

  • Research Site

    Ganzhou, 341099, China

  • Research Site

    Guangzhou, 510080, China

  • Research Site

    Jinan, 250013, China

  • Research Site

    Shenyang, 110001, China

  • Research Site

    Tianjin, 300060, China

  • Research Site

    Zhengzhou, 450008, China

  • Research Site

    Berlin, 12351, Germany

  • Research Site

    Cologne, 50937, Germany

  • Research Site

    Cologne, 51109, Germany

  • Research Site

    Hanover, 30625, Germany

  • Research Site

    München, D-80336, Germany

  • Research Site

    Beersheba, 84101, Israel

  • Research Site

    Jerusalem, 9103102, Israel

  • Research Site

    Jerusalem, 9112001, Israel

  • Research Site

    Kfar Saba, 4428164, Israel

  • Research Site

    Tel Aviv, 6423906, Israel

  • Research Site

    Tel Litwinsky, 52621, Israel

  • Research Site

    Florence, 50134, Italy

  • Research Site

    Meldola, 47014, Italy

  • Research Site

    Messina, 98158, Italy

  • Research Site

    Naples, 80131, Italy

  • Research Site

    Padua, 35128, Italy

  • Research Site

    Roma, 00168, Italy

  • Research Site

    Terni, 05100, Italy

  • Research Site

    Verona, 37124, Italy

  • Research Site

    Alicante, 03010, Spain

  • Research Site

    Barcelona, 08907, Spain

  • Research Site

    Córdoba, 14004, Spain

  • Research Site

    León, 24071, Spain

  • Research Site

    Madrid, 28040, Spain

  • Research Site

    Málaga, 29010, Spain

  • Research Site

    Murcia, 30008, Spain

  • Research Site

    Oviedo, 33011, Spain

  • Research Site

    Palma de Mallorca, 07010, Spain

  • Research Site

    Seville, 41013, Spain

  • Research Site

    Valencia, 46010, Spain

Conditions

Explore the condition pages connected to this study.