New hope for lung cancer patients when standard drug fails

NCT ID NCT06417814

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is for people with a specific type of advanced lung cancer (EGFR-mutated NSCLC) whose disease has gotten worse while taking the drug osimertinib. It will test whether a new drug called Dato-DXd, given alone or together with osimertinib, works better and is safer than standard platinum-based chemotherapy. The main goal is to see which treatment can keep the cancer from growing for the longest time.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Research Site
RECRUITING

Fayetteville, Arkansas, 72703, United States
Research Site
WITHDRAWN

Duarte, California, 91010, United States
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Fountain Valley, California, 92708, United States
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La Jolla, California, 92093, United States
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WITHDRAWN

Los Angeles, California, 90048, United States
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NOT_YET_RECRUITING

San Diego, California, 92123, United States
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Colorado Springs, Colorado, 80909, United States
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Fort Collins, Colorado, 80528, United States
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WITHDRAWN

Gainesville, Florida, 32608, United States
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Jacksonville, Florida, 32256, United States
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Athens, Georgia, 30607, United States
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NOT_YET_RECRUITING

Chicago, Illinois, 60611, United States
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Evanston, Illinois, 60201, United States
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Louisville, Kentucky, 40207, United States
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Baltimore, Maryland, 21201, United States
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Bethesda, Maryland, 20817, United States
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WITHDRAWN

Boston, Massachusetts, 02114, United States
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Boston, Massachusetts, 02215, United States
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NOT_YET_RECRUITING

Boston, Massachusetts, 02215, United States
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Detroit, Michigan, 48202, United States
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Kansas City, Missouri, 64132, United States
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Omaha, Nebraska, 68124, United States
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Morristown, New Jersey, 07960, United States
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Northfield, New Jersey, 08225, United States
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WITHDRAWN

New York, New York, 10016, United States
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New York, New York, 10065, United States
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The Bronx, New York, 10461, United States
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Maumee, Ohio, 43537, United States
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WITHDRAWN

Philadelphia, Pennsylvania, 19107, United States
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Pittsburgh, Pennsylvania, 15232, United States
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Chattanooga, Tennessee, 37404, United States
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Nashville, Tennessee, 37203, United States
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Fairfax, Virginia, 22031, United States
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WITHDRAWN

Seattle, Washington, 98104, United States
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Fitzroy, VIC3065, Australia
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Heidelberg, 3084, Australia
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Kogarah, 2217, Australia
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Liverpool, 2170, Australia
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Nedlands, 6009, Australia
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Port Macquarie, 2444, Australia
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St Leonards, 2065, Australia
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Westmead, 2145, Australia
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NOT_YET_RECRUITING

Woodville, 5011, Australia
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Woolloongabba, 4102, Australia
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Charleroi, 6060, Belgium
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Edegem, 2650, Belgium
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Ghent, 9000, Belgium
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Hasselt, 3500, Belgium
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Jette, 1090, Belgium
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La Louvière, 7100, Belgium
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Leuven, 3000, Belgium
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Namur, 5000, Belgium
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Roeselare, 8800, Belgium
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NOT_YET_RECRUITING

Barretos, 14784-400, Brazil
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NOT_YET_RECRUITING

Betim, 32671-550, Brazil
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NOT_YET_RECRUITING

Blumenau, 89010-340, Brazil
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NOT_YET_RECRUITING

Florianópolis, 88040-970, Brazil
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RECRUITING

Itajaí, 88301-220, Brazil
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NOT_YET_RECRUITING

Pelotas, 96020-080, Brazil
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NOT_YET_RECRUITING

Porto Alegre, 90035-074, Brazil
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NOT_YET_RECRUITING

Porto Alegre, 90470-340, Brazil
Research Site
NOT_YET_RECRUITING

Porto Alegre, 90610-000, Brazil
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NOT_YET_RECRUITING

Rio de Janeiro, 22250-905, Brazil
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NOT_YET_RECRUITING

Rio de Janeiro, 22281-100, Brazil
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NOT_YET_RECRUITING

Rio de Janeiro, 22775-001, Brazil
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NOT_YET_RECRUITING

São Paulo, 01323-900, Brazil
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NOT_YET_RECRUITING

São Paulo, 01327-001, Brazil
Research Site
RECRUITING

Brampton, Ontario, L6R 3J7, Canada
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WITHDRAWN

Newmarket, Ontario, L3Y 2P9, Canada
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Toronto, Ontario, M4N 3M5, Canada
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RECRUITING

Toronto, Ontario, M5G 1Z5, Canada
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Montreal, Quebec, H4A 3J1, Canada
Research Site
NOT_YET_RECRUITING

Québec, Quebec, G1R 2J6, Canada
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RECRUITING

Baoding, 071000, China
Research Site
RECRUITING

Beijing, 100005, China
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RECRUITING

Beijing, 100034, China
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Beijing, 100044, China
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Beijing, 100050, China
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RECRUITING

Beijing, 100142, China
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RECRUITING

Beijing, 100730, China
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Beijing, 101199, China
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Bengbu, 233004, China
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Changchun, 130012, China
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Changchun, 130021, China
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RECRUITING

Changsha, 410013, China
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Chengdu, 610041, China
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Deyang, 618000, China
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Ganzhou, 341099, China
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Guangzhou, 510180, China
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Hangzhou, 310003, China
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Hangzhou, 310022, China
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Hefei, 230001, China
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Hengyang, 421001, China
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Huaian, 223399, China
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Jinan, 250013, China
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Linyi, 276000, China
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Luoyang, 471003, China
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Luzhou, 646000, China
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Nanchang, 330006, China
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Nanjing, 210009, China
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Shanghai, 200433, China
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Shantou, China
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Shenyang, 110004, China
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Shenyang, 110042, China
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RECRUITING

Tianjin, 300201, China
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Tianjin, CN-300052, China
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Weifang, 261000, China
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Wuhan, 430060, China
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Zhengzhou, 450000, China
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RECRUITING

Zhengzhou, 450001, China
Research Site
RECRUITING

Zhengzhou, 450008, China
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RECRUITING

Angers, 49933, France
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RECRUITING

Avignon, 84902, France
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RECRUITING

Bordeaux, 33076, France
Research Site
NOT_YET_RECRUITING

Caen, 14000, France
Research Site
RECRUITING

Lille, 59037, France
Research Site
RECRUITING

Montpellier, 34298, France
Research Site
RECRUITING

Nantes, 44093, France
Research Site
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Paris, 75014, France
Research Site
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Paris, 75970, France
Research Site
RECRUITING

Pessac, 33604, France
Research Site
WITHDRAWN

Quimper, 29000, France
Research Site
RECRUITING

Toulon Armees, 83800, France
Research Site
RECRUITING

Toulouse, 31400, France
Research Site
RECRUITING

Tours, 37000, France
Research Site
RECRUITING

Villejuif, 94805, France
Research Site
NOT_YET_RECRUITING

Berlin, 12351, Germany
Research Site
NOT_YET_RECRUITING

Berlin-Zehlendorf, 14165, Germany
Research Site
WITHDRAWN

Bonn, 53127, Germany
Research Site
RECRUITING

Essen, 45122, Germany
Research Site
RECRUITING

Georgsmarienhütte, 49124, Germany
Research Site
NOT_YET_RECRUITING

Giessen, 35392, Germany
Research Site
RECRUITING

Großhansdorf, 22927, Germany
Research Site
RECRUITING

Hamburg, 20251, Germany
Research Site
RECRUITING

Hamburg, 21075, Germany
Research Site
WITHDRAWN

Heidelberg, 69126, Germany
Research Site
WITHDRAWN

Kempten, 87439, Germany
Research Site
RECRUITING

Löwenstein, 74245, Germany
Research Site
RECRUITING

Nuremberg, 90419, Germany
Research Site
RECRUITING

Oldenburg, 26121, Germany
Research Site
RECRUITING

Athens, 11526, Greece
Research Site
NOT_YET_RECRUITING

Athens, 11527, Greece
Research Site
WITHDRAWN

Athens, 12462, Greece
Research Site
RECRUITING

Athens, 18547, Greece
Research Site
WITHDRAWN

Heraklion, 71110, Greece
Research Site
RECRUITING

Thessaloniki, 552 36, Greece
Research Site
WITHDRAWN

Thessaloniki, 56249, Greece
Research Site
NOT_YET_RECRUITING

Thessaloniki, 57001, Greece
Research Site
NOT_YET_RECRUITING

Thessaloniki, 57010, Greece
Research Site
RECRUITING

Hong Kong, 999077, Hong Kong
Research Site
NOT_YET_RECRUITING

Hong Kong, 999077, Hong Kong
Research Site
RECRUITING

Hong Kong, Hong Kong
Research Site
NOT_YET_RECRUITING

Hong Kong, Hong Kong
Research Site
RECRUITING

Shatin, 00000, Hong Kong
Research Site
RECRUITING

Amravati, 444606, India
Research Site
RECRUITING

Bhubaneswar, 751019, India
Research Site
RECRUITING

Hyderabad, 500034, India
Research Site
RECRUITING

Kolhāpur, 416234, India
Research Site
NOT_YET_RECRUITING

Mumbai, 400012, India
Research Site
RECRUITING

Mysuru, 570017, India
Research Site
RECRUITING

Namakkal, 637001, India
Research Site
RECRUITING

Pune, 411001, India
Research Site
RECRUITING

Raipur, 492001, India
Research Site
RECRUITING

Rajasthan, 313001, India
Research Site
RECRUITING

Ranchi, 834001, India
Research Site
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Thane, 401107, India
Research Site
RECRUITING

Trivandrum, 695011, India
Research Site
RECRUITING

Varanasi, 221005, India
Research Site
RECRUITING

Beersheba, 8410101, Israel
Research Site
RECRUITING

Haifa, 3109601, Israel
Research Site
RECRUITING

Haifa, 34362, Israel
Research Site
RECRUITING

Jerusalem, 91031, Israel
Research Site
RECRUITING

Jerusalem, 91120, Israel
Research Site
RECRUITING

Kfar Saba, 4428164, Israel
Research Site
RECRUITING

Petah Tikva, 49100, Israel
Research Site
RECRUITING

Ramat Gan, 52621, Israel
Research Site
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Tel Aviv, 62748, Israel
Research Site
RECRUITING

Bari, 70124, Italy
Research Site
RECRUITING

Milan, 20141, Italy
Research Site
RECRUITING

Misterbianco, 95045, Italy
Research Site
RECRUITING

Monza, 20090, Italy
Research Site
RECRUITING

Naples, 80131, Italy
Research Site
RECRUITING

Orbassano, 10043, Italy
Research Site
RECRUITING

Padua, 35128, Italy
Research Site
NOT_YET_RECRUITING

Parma, 43126, Italy
Research Site
RECRUITING

Perugia, 06100, Italy
Research Site
RECRUITING

Roma, 00144, Italy
Research Site
RECRUITING

Rozzano, 20089, Italy
Research Site
RECRUITING

Verona, 37126, Italy
Research Site
RECRUITING

Bunkyō City, 113-8431, Japan
Research Site
RECRUITING

Bunkyō City, 113-8603, Japan
Research Site
RECRUITING

Fukuoka, 812-8582, Japan
Research Site
RECRUITING

Hiroshima, 734-8551, Japan
Research Site
RECRUITING

Iruma-Gun, 350-0495, Japan
Research Site
RECRUITING

Iwakuni-shi, 740-8510, Japan
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RECRUITING

Kobe, 650-0046, Japan
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RECRUITING

Kōtoku, 135-8550, Japan
Research Site
RECRUITING

Kumamoto, 860-8556, Japan
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RECRUITING

Kyoto, 602-8566, Japan
Research Site
RECRUITING

Matsuyama, 791-0280, Japan
Research Site
WITHDRAWN

Nagoya, 464-8681, Japan
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RECRUITING

Nagoya, 466-8560, Japan
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Niigata, 951-8566, Japan
Research Site
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Osaka, 534-0021, Japan
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Osaka, 541-8567, Japan
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Ōsaka-sayama, 589-8511, Japan
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Sendai, 981-0914, Japan
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Sunto-gun, 411-8777, Japan
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Toyoake-shi, 470-1192, Japan
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Utsunomiya, 320-0834, Japan
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RECRUITING

Wakayama, 641-8510, Japan
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Yokohama, 236-0051, Japan
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Yokohama, 241-8515, Japan
Research Site
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Alor Star, 05460, Malaysia
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Cheras, 56000, Malaysia
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Johor Bahru, 81100, Malaysia
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Kuala Lumpur, 59100, Malaysia
Research Site
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Kuala Selangor, 46050, Malaysia
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Kuching, 93586, Malaysia
Research Site
RECRUITING

Perai, 13700, Malaysia
Research Site
RECRUITING

Petaling Jaya, 47500, Malaysia
Research Site
WITHDRAWN

Amersfoort, 3813 TZ, Netherlands
Research Site
WITHDRAWN

Harderwijk, 3844 DG, Netherlands
Research Site
WITHDRAWN

Rotterdam, 3015 GD, Netherlands
Research Site
WITHDRAWN

Zutphen, 7207 AE, Netherlands
Research Site
RECRUITING

Bacolod, 6100, Philippines
Research Site
RECRUITING

Cebu City, 6000, Philippines
Research Site
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Davao City, 8000, Philippines
Research Site
RECRUITING

Manila, 1000, Philippines
Research Site
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Quezon, 1102, Philippines
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Quezon, 1104, Philippines
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San Juan City, 1500, Philippines
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Katowice, 40-519, Poland
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Krakow, 30-727, Poland
Research Site
RECRUITING

Lodz, 90-302, Poland
Research Site
RECRUITING

Olsztyn, 10-357, Poland
Research Site
RECRUITING

Poznan, 60-569, Poland
Research Site
WITHDRAWN

Braga, 4710, Portugal
Research Site
WITHDRAWN

Lisbon, 1500-650, Portugal
Research Site
WITHDRAWN

Loures, 2674-514, Portugal
Research Site
WITHDRAWN

Porto, 4099-001, Portugal
Research Site
WITHDRAWN

Porto, 4200-072, Portugal
Research Site
WITHDRAWN

Craiova, 200385, Romania
Research Site
WITHDRAWN

Craiova, 200542, Romania
Research Site
RECRUITING

Singapore, 168583, Singapore
Research Site
RECRUITING

Singapore, 217562, Singapore
Research Site
RECRUITING

Singapore, 308433, Singapore
Research Site
RECRUITING

Busan, 48108, South Korea
Research Site
RECRUITING

Chungcheongbuk-do, 28644, South Korea
Research Site
RECRUITING

Goyang-si, 10408, South Korea
Research Site
RECRUITING

Gyeonggi-do, 13620, South Korea
Research Site
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Jinju, 52727, South Korea
Research Site
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Seoul, 03080, South Korea
Research Site
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Seoul, 03722, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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Seoul, 5505, South Korea
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Suwon, 16247, South Korea
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A Coruña, 15009, Spain
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Barakaldo, 48903, Spain
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Barcelona, 08003, Spain
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Barcelona, 08041, Spain
Research Site
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El Palmar, 30120, Spain
Research Site
RECRUITING

L'Hospitalet de Llobregat, 08908, Spain
Research Site
RECRUITING

Madrid, 28027, Spain
Research Site
NOT_YET_RECRUITING

Madrid, 28046, Spain
Research Site
NOT_YET_RECRUITING

Majadahonda, 28222, Spain
Research Site
RECRUITING

Málaga, 29004, Spain
Research Site
NOT_YET_RECRUITING

Oviedo, 33006, Spain
Research Site
RECRUITING

Palma de Mallorca, 7120, Spain
Research Site
RECRUITING

Pamplona, 31008, Spain
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RECRUITING

Santander, 39008, Spain
Research Site
RECRUITING

Santiago de Compostela-Coruña, 15706, Spain
Research Site
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Seville, 41014, Spain
Research Site
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Valencia, 46010, Spain
Research Site
RECRUITING

Valencia, 46026, Spain
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Valladolid, 47003, Spain
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Changhua, 50006, Taiwan
Research Site
RECRUITING

Kaohsiung City, 80756, Taiwan
Research Site
RECRUITING

New Taipei City, 23561, Taiwan
Research Site
RECRUITING

Taichung, 404, Taiwan
Research Site
RECRUITING

Taichung, 40705, Taiwan
Research Site
RECRUITING

Tainan, 70403, Taiwan
Research Site
RECRUITING

Tainan, 73657, Taiwan
Research Site
RECRUITING

Taipei, 100, Taiwan
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RECRUITING

Taipei, 110, Taiwan
Research Site
RECRUITING

Taipei, 112, Taiwan
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RECRUITING

Bangkok, 10330, Thailand
Research Site
RECRUITING

Bangkok, 10400, Thailand
Research Site
RECRUITING

Bangkok, 10700, Thailand
Research Site
RECRUITING

Chiang Mai, 50200, Thailand
Research Site
RECRUITING

Hat Yai, 90110, Thailand
Research Site
RECRUITING

Khon Kaen, 40002, Thailand
Research Site
RECRUITING

Pathum Thani, 12120, Thailand
Research Site
RECRUITING

Birmingham, B9 5SS, United Kingdom
Research Site
RECRUITING

Cambridge, CB2 0QQ, United Kingdom
Research Site
RECRUITING

Glasgow, G12 0YN, United Kingdom
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RECRUITING

Leicester, LE1 5WW, United Kingdom
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RECRUITING

London, EC1A 7BE, United Kingdom
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Manchester, M20 4BX, United Kingdom
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RECRUITING

Middlesbrough, TS4 3BW, United Kingdom
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RECRUITING

Hanoi, 100000, Vietnam

Conditions

Explore the condition pages connected to this study.

METASTATIC NON-SMALL CELL LUNG CANCER