Lung cancer drug cocktail trial ends early – what we know

NCT ID NCT04619433

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This phase 3 trial tested a combination of three drugs—camrelizumab (an immunotherapy), famitinib (a targeted therapy), and standard chemotherapy—in 48 people with advanced non-squamous non-small-cell lung cancer that did not have certain genetic changes. The study aimed to see if the combo worked better than chemo alone, but it was terminated early, so we have limited information on its effectiveness or safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Camrelizumab (an immunotherapy drug), Famitinib (a targeted therapy), and chemotherapy (pemetrexed and carboplatin)

What this could lead to

If successful, this combination could offer a new treatment option for people with a common type of lung cancer that lacks certain genetic mutations.

What could go wrong

The trial was terminated early with only 48 participants, so results are limited. It is unclear if the combination is safe or effective, and side effects from multiple drugs can be significant.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Cancer Hosipital

    Beijing, Beijing Municipality, 100089, China

  • Henan Cancer Hospital

    Zhengzhou, Henan, 450003, China

  • Hubei Cancer Hospita

    Wuhan, Hubei, 430079, China

  • Shanghai Lung Hospital

    Shanghai, Shanghai Municipality, 200433, China

  • Shengjing Hospita of China Medical University

    Shenyang, Liaoning, 110022, China

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, Tianjin Municipality, 300060, China

  • West China Hospital,Sichuan University

    Chengdu, Sichuan, 610000, China