Targeted attack on lung cancer before surgery: could new drug combo stop recurrence?

NCT ID NCT05472623

Summary

This study aimed to test whether giving a targeted drug called adagrasib, alone or combined with an immunotherapy drug (nivolumab), before surgery could better treat operable non-small cell lung cancer with a specific KRAS G12C mutation. The goal was to see if this approach could kill more of the tumor before it was removed, potentially reducing the chance of the cancer coming back. The trial was designed for patients with stage IB-IIIA lung cancer but was withdrawn before any participants were enrolled.

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Contacts and locations

Locations

  • Johns Hopkins

    Baltimore, Maryland, 21231, United States

Conditions

Explore the condition pages connected to this study.