Radiation plus immunotherapy before lung surgery shows promise in early trial

NCT ID NCT05500092

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether adding a precise, high-dose form of radiation (SBRT) to standard chemotherapy and immunotherapy (nivolumab) before surgery can improve outcomes for people with stage IIA to IIIB non-small cell lung cancer. About 17 participants were randomly assigned to receive either the standard combination or the combination plus radiation. The main goal is to see how many patients have no cancer cells left in their removed tumor tissue after treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Montefiore Medical Center-Albert Einstein College of Medicine

    The Bronx, New York, 10461, United States

  • Penn State Health Milton S. Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • Washington University in St. Louis

    St Louis, Missouri, 63130, United States

  • White Plains Hospital (WPH)

    White Plains, New York, 10601, United States