Pill vs. placebo: major trial aims to stop lung Cancer's return

NCT ID NCT02511106

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a daily pill called AZD9291 can prevent lung cancer from returning in patients who have had their tumor completely removed by surgery. The trial involves 682 patients with early-stage lung cancer who have a specific genetic mutation. Patients are randomly assigned to receive either the real pill or a placebo (sugar pill) for up to three years to see which group stays cancer-free longer.

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Contacts and locations

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Locations

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Los Angeles, California, 90048, United States
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Santa Monica, California, 90404, United States
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Santa Rosa, California, 95403, United States
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Torrance, California, 90505, United States
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Grand Junction, Colorado, 81501, United States
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New Haven, Connecticut, 06520, United States
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Norwalk, Connecticut, 06856, United States
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Fort Myers, Florida, 33901, United States
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Pembroke Pines, Florida, 33028, United States
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St. Petersburg, Florida, 33705, United States
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Athens, Georgia, 30607, United States
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Honolulu, Hawaii, 96819, United States
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Chicago, Illinois, 60612, United States
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Elk Grove Village, Illinois, 60007, United States
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Bethesda, Maryland, 20817, United States
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Brick, New Jersey, 08724, United States
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Florham Park, New Jersey, 07932, United States
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Mineola, New York, 11501, United States
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Pawtucket, Rhode Island, 02860, United States
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Chattanooga, Tennessee, 37404, United States
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Nashville, Tennessee, 37203, United States
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San Antonio, Texas, 78229, United States
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Fort Belvoir, Virginia, 22060, United States
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Bedford Park, 5042, Australia
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Camperdown, 2050, Australia
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Darlinghurst, 2010, Australia
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Heidelberg, 3084, Australia
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Kogarah, 2217, Australia
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Kurralta Park, 5037, Australia
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Woolloongabba, 4102, Australia
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Brussels, 1090, Belgium
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Brussels, 1200, Belgium
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Ghent, 9000, Belgium
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Kortrijk, 8500, Belgium
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Barretos, 14784-400, Brazil
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Cachoeira de Itapemirim, 29308-055, Brazil
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Curitiba, 81520-060, Brazil
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Florianópolis, 88034-000, Brazil
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Fortaleza, 60810-180, Brazil
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Lajeado, 95900000, Brazil
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Porto Alegre, 90619-900, Brazil
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Rio de Janeiro, 22793-080, Brazil
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Salvador, 40170-110, Brazil
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São José do Rio Preto, 15025-100, Brazil
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São Paulo, 01321-001, Brazil
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Toronto, Ontario, M5G 2M9, Canada
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Beijing, 100029, China
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Beijing, 100142, China
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Beijing, 100210, China
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Beijing, 100730, China
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Changchun, 130012, China
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Changchun, 130021, China
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Dalian, 116027, China
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Guangzhou, 510060, China
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Guangzhou, 510120, China
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Guangzhou, 510180, China
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Hangzhou, 310003, China
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Hangzhou, 310009, China
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Hangzhou, 310022, China
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Kunming, 650118, China
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Nanjing, 210029, China
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Nanning, 530021, China
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Shanghai, 200030, China
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Shanghai, 200032, China
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Shanghai, 200072, China
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Shenyang, 110001, China
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Suzhou, 215006, China
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Tianjin, 300050, China
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Tianjin, 300051, China
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Tianjin, 300060, China
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Ürümqi, 830000, China
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Xi'an, 710061, China
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Xiamen, 361004, China
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Yangzhou, 225001, China
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Zhengzhou, 450008, China
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Bron, 69677, France
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Lille, 59000, France
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Limoges, 87042, France
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Lyon, 69008, France
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Paris, 75020, France
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Aachen, 52074, Germany
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Berlin, 12351, Germany
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Berlin, 13125, Germany
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Berlin, 13359, Germany
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Cologne, 51109, Germany
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Coswig, 01640, Germany
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Gauting, 82131, Germany
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Gerlingen, 70839, Germany
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Großhansdorf, 22927, Germany
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Halle, 06120, Germany
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Hamburg, 20251, Germany
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Homburg, 66421, Germany
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Immenhausen, 34376, Germany
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Kassel, 34125, Germany
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Lübeck, 23538, Germany
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Würzburg, 97074, Germany
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Hong Kong, 150001, Hong Kong
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Hong Kong, Hong Kong
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King's Park, 150001, Hong Kong
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Budapest, 1083, Hungary
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Budapest, 1121, Hungary
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Deszk, 6772, Hungary
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Székesfehérvár, 8000, Hungary
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Törökbálint, 2045, Hungary
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Beersheba, 8410101, Israel
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Haifa, 31999, Israel
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Jerusalem, 91120, Israel
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Kfar Saba, 4428164, Israel
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Petah Tikva, 4941492, Israel
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Ramat Gan, 5262000, Israel
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Tel Aviv, 6423906, Israel
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Bari, 70124, Italy
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Bergamo, 24127, Italy
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Bologna, 40138, Italy
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Cremona, 26100, Italy
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Florence, 50134, Italy
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Lucca, 55100, Italy
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Meldola, 47014, Italy
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Milan, 20132, Italy
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Milan, 20141, Italy
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Milan, 20162, Italy
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Novara, 28100, Italy
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Orbassano, 10043, Italy
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Padua, 35128, Italy
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Parma, 43126, Italy
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Roma, 00152, Italy
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Bunkyō City, 113-8431, Japan
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Fukuoka, 812-8582, Japan
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Hirakata-shi, 573-1191, Japan
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Hiroshima, 730-8518, Japan
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Hiroshima, 734-8551, Japan
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Kanazawa, 920-8641, Japan
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Kashiwa, 277-8577, Japan
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Kitakyushu-shi, 807-8555, Japan
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Kobe, 650-0047, Japan
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Kurume-shi, 830-0011, Japan
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Matsuyama, 791-0280, Japan
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Nagoya, 453-8511, Japan
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Niigata, 951-8566, Japan
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Osakasayama-shi, 589-8511, Japan
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Sagamihara-shi, 252-0375, Japan
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Sakaishi, 591-8555, Japan
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Sasebo-shi, 857-8511, Japan
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Sendai, 980-0873, Japan
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Shinjuku-ku, 160-0023, Japan
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Sunto-gun, 411-8777, Japan
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Ube-shi, 755-0241, Japan
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Yokohama, 240-8555, Japan
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Yokohama, 241-8515, Japan
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Yonago-shi, 683-8504, Japan
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Amsterdam, 1081 HV, Netherlands
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Arnhem, 6815 AD, Netherlands
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Hoofddorp, 2134 TM, Netherlands
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Zwolle, 8025 AB, Netherlands
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Krakow, 31-202, Poland
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Lodz, 90-302, Poland
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Otwock, 05-400, Poland
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Poznan, 60-569, Poland
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Racibórz, 47-400, Poland
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Warsaw, 02-781, Poland
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Wieliszew, 05-135, Poland
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Bucharest, 031422, Romania
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Bucharest, 050098, Romania
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Cluj-Napoca, 400015, Romania
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Craiova, 200385, Romania
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Focşani, 620165, Romania
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Iași, 700483, Romania
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Timișoara, 300210, Romania
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Arkhangelsk, 163045, Russia
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Kazan', 420029, Russia
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Moscow, 115478, Russia
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Moscow, 143423, Russia
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Obninsk, 249036, Russia
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Omsk, 644013, Russia
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Pyatigorsk, 357502, Russia
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Rostov-on-Don, 344037, Russia
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Ryazan, 390011, Russia
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Saint Petersburg, 194291, Russia
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Saint Petersburg, 195271, Russia
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Saint Petersburg, 197022, Russia
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Saint Petersburg, 197758, Russia
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Saint Petersburg, 198255, Russia
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Cheongju-si, 28644, South Korea
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Seoul, 02841, South Korea
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Seoul, 05030, South Korea
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Seoul, 138-736, South Korea
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Seoul, 156-707, South Korea
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Seoul, 6351, South Korea
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Suwon, 16247, South Korea
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Suwon, 16499, South Korea
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A Coruña, 15006, Spain
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Barcelona, 08041, Spain
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Donostia / San Sebastian, 20014, Spain
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Elche, 03203, Spain
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Las Palmas de Gran Canaria, 35016, Spain
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Madrid, 08035, Spain
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Madrid, 28007, Spain
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Madrid, 28040, Spain
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Madrid, 28046, Spain
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Majadahonda, 28222, Spain
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Málaga, 29010, Spain
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Valencia, 46010, Spain
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Valencia, 46026, Spain
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Zaragoza, 50009, Spain
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Linköping, 581 85, Sweden
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Changhua, 50006, Taiwan
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Putzu City, 0613, Taiwan
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Taichung, 402, Taiwan
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Taichung, 40705, Taiwan
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Tainan, 70403, Taiwan
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Tainan, 73657, Taiwan
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Taipei, 10002, Taiwan
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Taipei, 112, Taiwan
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Taoyuan District, 333, Taiwan
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Bangkok, 10330, Thailand
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Bangkok, 10700, Thailand
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Chiang Rai, 57000, Thailand
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Khon Kaen, 40002, Thailand
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Mueang, 50200, Thailand
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Phitsanulok, 65000, Thailand
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Songkhla, 90110, Thailand
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Ankara, 06280, Turkey (Türkiye)
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Ankara, 6500, Turkey (Türkiye)
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Bursa, 16059, Turkey (Türkiye)
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Istanbul, 34069, Turkey (Türkiye)
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Istanbul, 34093, Turkey (Türkiye)
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Istanbul, 34098, Turkey (Türkiye)
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Istanbul, 34722, Turkey (Türkiye)
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Izmir, 35100, Turkey (Türkiye)
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Dnipro, 49102, Ukraine
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Lviv, 79031, Ukraine
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Sumy, 40022, Ukraine
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Uzhhorod, 88000, Ukraine
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Vinnytsia, 21029, Ukraine
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Zaporizhzhia, 69040, Ukraine
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Hanoi, 100000, Vietnam
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Hanoi, 10000, Vietnam
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Ho Chi Minh City, 70000, Vietnam

Conditions

Explore the condition pages connected to this study.

STAGE IB-IIIA NON-SMALL CELL LUNG CARCINOMA