Pill vs. placebo: 3-Year fight to keep early lung cancer from coming back

NCT ID NCT05120349

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This global study is testing whether taking a daily pill called osimertinib for three years can prevent early-stage lung cancer from returning after surgery. It involves 390 adults whose lung cancer has been completely removed and has a specific genetic marker (EGFR mutation). Participants are randomly assigned to receive either the real pill or a placebo to compare outcomes.

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Contacts and locations

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Locations

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Anchorage, Alaska, 99508, United States
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Los Angeles, California, 90024, United States
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Orange, California, 92868, United States
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Grand Junction, Colorado, 81501, United States
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Newark, Delaware, 19713, United States
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Atlanta, Georgia, 30322, United States
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Chicago, Illinois, 60612, United States
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Frederick, Maryland, 21702, United States
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Morristown, New Jersey, 07960, United States
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Flushing, New York, 11355, United States
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New York, New York, 10032, United States
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New York, New York, 10065, United States
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White Plains, New York, 10601, United States
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Houston, Texas, 77030, United States
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Fort Belvoir, Virginia, 22060, United States
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Buenos Aires, C1431FWO, Argentina
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CABA, C1012AAR, Argentina
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Cipolletti, 8234, Argentina
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La Plata, 1900, Argentina
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Rosario, 2000, Argentina
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Rosario, S2000CVB, Argentina
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S.C. de Bariloche, 8400, Argentina
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Barretos, 14784-400, Brazil
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Belo Horizonte, 30380-090, Brazil
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Porto Alegre, 90610-000, Brazil
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Recife, 52010-075, Brazil
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Rio de Janeiro, 22271-110, Brazil
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São Paulo, 01327-001, Brazil
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São Paulo, 04501-000, Brazil
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Vancouver, British Columbia, V5Z 1M9, Canada
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Montreal, Quebec, H4A 3J1, Canada
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Toronto, M5G 2M9, Canada
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Beijing, 100005, China
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Beijing, 100029, China
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Beijing, 100142, China
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Beijing, 100210, China
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Beijing, 100730, China
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Beijing, 102218, China
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Changchun, 130012, China
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Changsha, 410013, China
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Changsha, 430033, China
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Chengdu, 610000, China
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Fuzhou, 350014, China
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Guangzhou, 510060, China
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Guangzhou, 510100, China
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Hangzhou, 310022, China
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Harbin, 150049, China
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Jinan, 250117, China
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Nanjing, 210029, China
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Shanghai, 200030, China
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Shanghai, 200032, China
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Shenzhen, 518116, China
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Suzhou, 215006, China
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Taiyuan, 030000, China
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Xi'an, 710061, China
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Xintai, 54031, China
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Yangzhou, 225001, China
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Zhengzhou, 450008, China
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Berlin, 13125, Germany
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Esslingen am Neckar, 73730, Germany
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Georgsmarienhütte, 49124, Germany
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Lübeck, 23538, Germany
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München, 81377, Germany
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Würzburg, 97067, Germany
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Bari, 70124, Italy
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Catania, 95100, Italy
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Florence, 50134, Italy
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Genova, 16132, Italy
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Milan, 20141, Italy
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Naples, 80131, Italy
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Padua, 35128, Italy
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Parma, 43100, Italy
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Roma, 00144, Italy
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Chiba, 260-0877, Japan
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Fukuoka, 812-8582, Japan
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Hiroshima, 734-8551, Japan
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Kashiwa, 227-8577, Japan
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Kōtoku, 135-8550, Japan
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Kyoto, 606-8507, Japan
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Niigata, 951-8566, Japan
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Osaka, 541-8567, Japan
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Sakai, 590-0197, Japan
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Sendai, 981-0914, Japan
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Shinjuku-ku, 160-0023, Japan
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Sunto-gun, 411-8777, Japan
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Wakayama, 641-8510, Japan
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Kuala Lumpur, 59100, Malaysia
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Kuala Selangor, 46050, Malaysia
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Kuching, 93586, Malaysia
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Pulau Pinang, 10450, Malaysia
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Poznan, 60-569, Poland
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Warsaw, 01-138, Poland
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Bucharest, 022328, Romania
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Bucharest, 050098, Romania
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Perm, 614990, Russia
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Saint Petersburg, 191036, Russia
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Singapore, 169610, Singapore
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Singapore, 308433, Singapore
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Daegu, 42415, South Korea
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Jinju, 52727, South Korea
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Seoul, 03082, South Korea
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Seoul, 05505, South Korea
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Seoul, 07061, South Korea
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Suwon, 16247, South Korea
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Suwon, 16499, South Korea
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Barcelona, 08041, Spain
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Málaga, 29010, Spain
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Valencia, 46010, Spain
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Vigo, 36312, Spain
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Zaragoza, 50009, Spain
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Taichung, 40201, Taiwan
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Taichung, 40705, Taiwan
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Tainan, 70403, Taiwan
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Taipei, 100, Taiwan
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Taipei, 11217, Taiwan
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Taipei, 114, Taiwan
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Taipei, 235, Taiwan
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Taoyuan District, 333, Taiwan
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Bangkok, 10300, Thailand
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Bangkok, 10330, Thailand
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Bangkok, 10700, Thailand
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Hat Yai, 90110, Thailand
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Khon Kaen, 40002, Thailand
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Muang, 50200, Thailand
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Ankara, 06010, Turkey (Türkiye)
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Bursa, 16059, Turkey (Türkiye)
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Istanbul, Turkey (Türkiye)
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Izmir, 35040, Turkey (Türkiye)
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Kadıkoy/Istanbul, 34722, Turkey (Türkiye)
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Birmingham, B9 5SS, United Kingdom
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Blackpool, FY3 8NR, United Kingdom
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London, SE1 9RT, United Kingdom
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London, SW10 9NH, United Kingdom
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London, SW3 6NP, United Kingdom
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Nottingham, NG5 1PB, United Kingdom
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Wythenshawe, M23 9LT, United Kingdom
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Hanoi, 100000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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Hồ Chí Minh, 700000, Vietnam

Conditions

Explore the condition pages connected to this study.

NON-SMALL CELL LUNG CANCER