Scientists test new drug duo in battle against Tough-to-Treat lung cancer

NCT ID NCT01638546

Summary

This study tested whether adding a new drug called veliparib to an existing chemotherapy (temozolomide) works better for people with small cell lung cancer that has come back or stopped responding to prior treatment. The goal was to see if the combination could help control the cancer for longer. About 100 patients were randomly assigned to receive either the two-drug combo or the chemotherapy plus a placebo pill.

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Contacts and locations

Locations

  • Case Western Reserve University

    Cleveland, Ohio, 44106, United States

  • Emory University Hospital/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Johns Hopkins Bayview Medical Center

    Baltimore, Maryland, 21224, United States

  • Johns Hopkins University/Sidney Kimmel Cancer Center

    Baltimore, Maryland, 21287, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Basking Ridge

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Nassau

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Sleepy Hollow

    Sleepy Hollow, New York, 10591, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

  • VCU Massey Comprehensive Cancer Center

    Richmond, Virginia, 23298, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.