Major trial tests if new drug duo can extend lives in advanced lung cancer

NCT ID NCT03164616

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study tested whether adding one or two immunotherapy drugs (durvalumab and tremelimumab) to standard chemotherapy works better than chemotherapy alone for people newly diagnosed with advanced non-small cell lung cancer that has spread. It involved over 1,100 patients worldwide and aimed to see if the new combinations help patients live longer or keep the cancer from growing for a longer time.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Research Site

Phoenix, Arizona, 85054, United States
Research Site

Bakersfield, California, 93309, United States
Research Site

Santa Monica, California, 90404, United States
Research Site

Fort Myers, Florida, 33901, United States
Research Site

Jacksonville, Florida, 32224, United States
Research Site

St. Petersburg, Florida, 33705, United States
Research Site

West Palm Beach, Florida, 33401, United States
Research Site

Louisville, Kentucky, 40202, United States
Research Site

Kansas City, Missouri, 64132, United States
Research Site

Canton, Ohio, 44710, United States
Research Site

Pittsburgh, Pennsylvania, 15212, United States
Research Site

Chattanooga, Tennessee, 37404, United States
Research Site

Nashville, Tennessee, 37203, United States
Research Site

Fort Worth, Texas, 76104, United States
Research Site

Houston, Texas, 77090, United States
Research Site

Richmond, Virginia, 23298, United States
Research Site

Barretos, 14784-400, Brazil
Research Site

Belo Horizonte, 30380-472, Brazil
Research Site

Curitiba, 81520-060, Brazil
Research Site

Porto Alegre, 90035-003, Brazil
Research Site

Porto Alegre, 90610-000, Brazil
Research Site

Porto Alegre, 91350-200, Brazil
Research Site

Ribeirão Preto, 14015-140, Brazil
Research Site

Rio de Janeiro, 20231-050, Brazil
Research Site

Santo André, 09060-650, Brazil
Research Site

Santo André, 09080-110, Brazil
Research Site

São José do Rio Preto, 15090-000, Brazil
Research Site

São Paulo, 01209-000, Brazil
Research Site

São Paulo, 01246-000, Brazil
Research Site

São Paulo, 03102-002, Brazil
Research Site

Plovdiv, 4000, Bulgaria
Research Site

Plovdiv, 4004, Bulgaria
Research Site

Sofia, 1330, Bulgaria
Research Site

Sofia, 1431, Bulgaria
Research Site

Sofia, 1618, Bulgaria
Research Site

Sofia, 1784, Bulgaria
Research Site

Varna, 9010, Bulgaria
Research Site

Beijing, 100021, China
Research Site

Beijing, 100142, China
Research Site

Changchun, 130012, China
Research Site

Changsha, 410013, China
Research Site

Fuzhou, 350014, China
Research Site

Guangzhou, 510080, China
Research Site

Hangzhou, 310022, China
Research Site

Harbin, 150081, China
Research Site

Hefei, 230601, China
Research Site

Kunming, CN-650034, China
Research Site

Linyi, 276000, China
Research Site

Liuchow, 545006, China
Research Site

Nanjing, 210009, China
Research Site

Qingdao, 110016, China
Research Site

Shanghai, 200030, China
Research Site

Shanghai, 200032, China
Research Site

Shanghai, 200080, China
Research Site

Shantou, 515041, China
Research Site

Wuhan, 430022, China
Research Site

Wuhan, 430079, China
Research Site

Xining, 810001, China
Research Site

Yangzhou, 225001, China
Research Site

Zhanjiang, 524001, China
Research Site

Zhengzhou, 450008, China
Research Site

Zhengzhou, 450052, China
Research Site

Berlin, 13125, Germany
Research Site

Essen, 45122, Germany
Research Site

Freiburg im Breisgau, 79106, Germany
Research Site

Gauting, 82131, Germany
Research Site

Hamburg, 20251, Germany
Research Site

Hamburg, 21075, Germany
Research Site

Heidelberg, 69126, Germany
Research Site

Immenhausen, 34376, Germany
Research Site

Mainz, 55131, Germany
Research Site

Oldenburg, 26121, Germany
Research Site

Würzburg, 97067, Germany
Research Site

Shatin, 00000, Hong Kong
Research Site

Budapest, 1083, Hungary
Research Site

Budapest, 1121, Hungary
Research Site

Kecskemét, 6000, Hungary
Research Site

Miskolc, 3529, Hungary
Research Site

Törökbálint, 2045, Hungary
Research Site

Bunkyō City, 113-8603, Japan
Research Site

Chūōku, 104-0045, Japan
Research Site

Fukuoka, 812-8582, Japan
Research Site

Hiroshima, 730-0011, Japan
Research Site

Iwakuni-shi, 740-8510, Japan
Research Site

Kanazawa, 920-8641, Japan
Research Site

Kashiwa, 227-8577, Japan
Research Site

Kōtoku, 135-8550, Japan
Research Site

Kurume-shi, 830-0011, Japan
Research Site

Matsuyama, 790-0007, Japan
Research Site

Okayama, 700-8558, Japan
Research Site

Okayama, 700-8607, Japan
Research Site

Sapporo, 003-0804, Japan
Research Site

Sayama, 589-8511, Japan
Research Site

Sunto-gun, 411-8777, Japan
Research Site

Toyoake-shi, 470-1101, Japan
Research Site

Ube-shi, 755-0241, Japan
Research Site

Yokohama, 236-0004, Japan
Research Site

Yokohama, 241-8515, Japan
Research Site

Aguascalientes, 20230, Mexico
Research Site

Cuautitlán Izcalli, 54769, Mexico
Research Site

Guadalajara, 44280, Mexico
Research Site

Mexico City, 0 3100, Mexico
Research Site

México, 04739, Mexico
Research Site

México, 14080, Mexico
Research Site

Monterrey, 64060, Mexico
Research Site

Monterrey, 64460, Mexico
Research Site

Tuxtla Gutiérrez, 29030, Mexico
Research Site

Arequipa, AREQUIPA01, Peru
Research Site

Lima, L27, Peru
Research Site

Lima, LIMA 29, Peru
Research Site

Lima, LIMA 34, Peru
Research Site

Lima, LIMA 41, Peru
Research Site

San Isidro, 27, Peru
Research Site

Olsztyn, 10-357, Poland
Research Site

Tomaszów Mazowiecki, 97-200, Poland
Research Site

Warsaw, 02-781, Poland
Research Site

Wodzisław Śląski, 44-300, Poland
Research Site

Moscow, 105229, Russia
Research Site

Moscow, 115280, Russia
Research Site

Moscow, 115478, Russia
Research Site

Moscow, 125367, Russia
Research Site

Omsk, 644013, Russia
Research Site

Saint Petersburg, 194291, Russia
Research Site

Saint Petersburg, 195271, Russia
Research Site

Saint Petersburg, 196603, Russia
Research Site

Saint Petersburg, 197758, Russia
Research Site

Cape Town, 7570, South Africa
Research Site

Durban, 4091, South Africa
Research Site

Johannesburg, 0001, South Africa
Research Site

Parktown, 2193, South Africa
Research Site

Pretoria, 0001, South Africa
Research Site

Rondebosch, 7700, South Africa
Research Site

Vereeniging, 1930, South Africa
Research Site

Busan, 47392, South Korea
Research Site

Chungcheongbuk-do, 28644, South Korea
Research Site

Daegu, 42415, South Korea
Research Site

Incheon, 21565, South Korea
Research Site

Seongnam-si, 13620, South Korea
Research Site

Seoul, 05505, South Korea
Research Site

Seoul, 06591, South Korea
Research Site

Seoul, 120-752, South Korea
Research Site

Seoul, 6351, South Korea
Research Site

Ulsan, 44033, South Korea
Research Site

Changhua, 50006, Taiwan
Research Site

Kaohsiung City, 82445, Taiwan
Research Site

Kaohsiung City, 83301, Taiwan
Research Site

Taichung, 40447, Taiwan
Research Site

Taichung, 40705, Taiwan
Research Site

Tainan, 70403, Taiwan
Research Site

Taipei, 10002, Taiwan
Research Site

Taipei, 112, Taiwan
Research Site

Taipei, 235, Taiwan
Research Site

Taoyuan District, 333, Taiwan
Research Site

Bangkok, 10210, Thailand
Research Site

Bangkok, 10330, Thailand
Research Site

Bangkok, 10400, Thailand
Research Site

Muang, 50200, Thailand
Research Site

Songkhla, 90110, Thailand
Research Site

Dnipro, 49102, Ukraine
Research Site

Ivano-Frankivsk, 76018, Ukraine
Research Site

Kirovohrad, 25006, Ukraine
Research Site

Kyiv, 03022, Ukraine
Research Site

Kyiv, 03115, Ukraine
Research Site

Lviv, 79031, Ukraine
Research Site

Odesa, 65055, Ukraine
Research Site

Sumy, 40022, Ukraine
Research Site

Vinnytsia, 21029, Ukraine
Research Site

Zaporizhzhia, 69040, Ukraine
Research Site

Leicester, LE1 5WW, United Kingdom
Research Site

London, EC1M 6BQ, United Kingdom
Research Site

London, NW1 2PG, United Kingdom
Research Site

London, W6 8RF, United Kingdom
Research Site

Manchester, M20 4BX, United Kingdom
Research Site

Hanoi, 100000, Vietnam
Research Site

Ho Chi Minh City, 700000, Vietnam

Conditions

Explore the condition pages connected to this study.

NON-SMALL CELL LUNG CANCER (NSCLC)