New drug shows promise in slowing advanced lung cancer

NCT ID NCT02296125

Completed Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large, completed study tested a new drug called AZD9291 (osimertinib) against standard first-line treatments for adults with advanced non-small cell lung cancer that has a specific genetic mutation (EGFR). The goal was to see if the new drug could better control the cancer and delay its progression. Researchers compared how long patients lived without their cancer getting worse and monitored side effects and quality of life.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Anaheim, California, 92801, United States
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Santa Rosa, California, 95403, United States
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West Hills, California, 91307, United States
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Tampa, Florida, 33612, United States
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Atlanta, Georgia, 30318, United States
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Atlanta, Georgia, 30322, United States
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Marietta, Georgia, 30060, United States
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Louisville, Kentucky, 40202, United States
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Bethesda, Maryland, 20817, United States
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Boston, Massachusetts, 02215, United States
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Minneapolis, Minnesota, 55407, United States
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Lebanon, New Hampshire, 03756, United States
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Salisbury, North Carolina, 28144, United States
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Burlington, Vermont, 05401, United States
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Camperdown, 2050, Australia
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Chermside, 4032, Australia
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Clayton, 3168, Australia
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Heidelberg, 3084, Australia
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Kogarah, 2217, Australia
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Nedlands, 6009, Australia
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Woolloongabba, 4102, Australia
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Leuven, 3000, Belgium
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Liège, 4000, Belgium
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Roeselare, 8800, Belgium
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Porto Alegre, 90610-000, Brazil
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Sofia, 1330, Bulgaria
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Edmonton, Alberta, T6G 1Z2, Canada
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Hamilton, Ontario, L8V 5C2, Canada
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Ottawa, Ontario, K1H 8L6, Canada
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Toronto, Ontario, M4N 3M5, Canada
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Toronto, Ontario, M5G 1X5, Canada
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Toronto, Ontario, M5G 2M9, Canada
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Beijing, 100071, China
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Beijing, 100853, China
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Changchun, 130012, China
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Changchun, 130021, China
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Chongqing, 400037, China
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Chongqing, 400038, China
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Chongqing, 400042, China
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Fuzhou, 350025, China
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Guangzhou, 510080, China
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Hangzhou, 310022, China
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Nanjing, 210029, China
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Nanning, 530021, China
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Shanghai, 200433, China
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Shenyang, 110001, China
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Suzhou, 215006, China
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Ürümqi, 830000, China
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Wuhan, 430071, China
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Xi'an, 710038, China
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Xi'an, 710061, China
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Yangzhou, 225001, China
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Ostrava, 708 52, Czechia
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Caen, F-14033, France
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Créteil, 94010, France
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Lyon, 69373, France
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Nantes, 44202, France
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Toulon Naval, 83800, France
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Villejuif, 94805, France
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Bad Berka, 99437, Germany
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Berlin, 13125, Germany
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Gauting, 82131, Germany
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Halle, 06120, Germany
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Heidelberg, 69126, Germany
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Karlsruhe, 76137, Germany
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Lübeck, 23538, Germany
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München, 81925, Germany
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Villingen-Schwenningen, 78052, Germany
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Farkasgyepü, 8582, Hungary
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Gyöngyös - Mátraháza, 3200, Hungary
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Miskolc, 3529, Hungary
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Székesfehérvár, 8000, Hungary
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Tatabánya, 2800, Hungary
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Zalaegerszeg, 8900, Hungary
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Haifa, 31999, Israel
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Kfar Saba, 4428164, Israel
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Petah Tikva, 49100, Israel
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Tel Litwinsky, 52621, Israel
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Cremona, 26100, Italy
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Lecce, 73100, Italy
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Lecco, 23900, Italy
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Orbassano, 10043, Italy
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Parma, 43126, Italy
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Roma, 00144, Italy
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Sondrio, 23100, Italy
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Terni, 05100, Italy
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Chūōku, 104-0045, Japan
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Fukuoka, 812-8582, Japan
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Hirakata-shi, 573-1191, Japan
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Kanazawa, 920-8641, Japan
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Kashiwa, 277-8577, Japan
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Kobe, 650-0047, Japan
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Matsuyama, 791-0280, Japan
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Natori-shi, 981-1293, Japan
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Osaka, 541-8567, Japan
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Osakasayama-shi, 589-8511, Japan
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Sagamihara-shi, 252-0375, Japan
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Sakaishi, 591-8555, Japan
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Sendai, 980-0873, Japan
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Sunto-gun, 411-8777, Japan
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Yokohama, 232-0024, Japan
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Yokohama, 236-0051, Japan
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Yokohama, 240-8555, Japan
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Yokohama, 241-8515, Japan
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Kuala Lumpur, 59100, Malaysia
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Kuantan, 25100, Malaysia
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Kuching, 93586, Malaysia
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Cebu, 6000, Philippines
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Manila, 1000, Philippines
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Quezon City, 1100, Philippines
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Brzozoów, 36-200, Poland
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Otwock, 05-400, Poland
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Poznan, 60-569, Poland
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Szczecin, 70-891, Poland
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Warsaw, 02-781, Poland
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Amadora, 2720-276, Portugal
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Lisbon, 1769-001, Portugal
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Porto, 4200-072, Portugal
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Vila Nova de Gaia, 4434-502, Portugal
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Bucharest, 022328, Romania
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Bucharest, 050098, Romania
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Craiova, 200347, Romania
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Saint Petersburg, 197022, Russia
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Saint Petersburg, 197758, Russia
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Saint Petersburg, 198255, Russia
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Cheongju-si, 28644, South Korea
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Incheon, 405-760, South Korea
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Seongnam-si, 13620, South Korea
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Seoul, 02841, South Korea
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Seoul, 03722, South Korea
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Seoul, 06591, South Korea
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Seoul, 5030, South Korea
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A Coruña, 15006, Spain
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Barcelona, 08041, Spain
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Barcelona, 08221, Spain
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Barcelona, 08907, Spain
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Lleida, 25198, Spain
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Lugo, 27003, Spain
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Madrid, 28040, Spain
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Málaga, 29010, Spain
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Seville, 41014, Spain
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Zaragoza, 50009, Spain
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Linköping, 581 85, Sweden
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Lucerne, 6000, Switzerland
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Winterthur, 8401, Switzerland
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Zurich, 8091, Switzerland
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Kaohsiung City, 833, Taiwan
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Taichung, 402, Taiwan
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Tainan, 704, Taiwan
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Tainan, 73657, Taiwan
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Taoyuan, 333, Taiwan
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Bangkok, 10330, Thailand
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Bangkok, 10400, Thailand
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Bangkok, 10700, Thailand
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Hat Yai, 90110, Thailand
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Muang, 50200, Thailand
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Ankara, 6500, Turkey (Türkiye)
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Istanbul, 34069, Turkey (Türkiye)
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Izmir, 35100, Turkey (Türkiye)
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Dnipro, 49102, Ukraine
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Kryvyi Rih, 50048, Ukraine
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Lviv, 79031, Ukraine
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Sumy, 40022, Ukraine
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Edinburgh, EH4 2XU, United Kingdom
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London, NW1 2BU, United Kingdom
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Maidstone, ME16 9QQ, United Kingdom
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Withington, M20 4BX, United Kingdom
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Hanoi, 100000, Vietnam
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Hanoi, 10000, Vietnam
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Ho Chi Minh City, 70000, Vietnam

Conditions

Explore the condition pages connected to this study.

LOCALLY ADVANCED OR METASTATIC EGFR SENSITISING MUTATION POSITIVE NON SMALL CELL LUNG CANCER