Early trial tests new combo for Tough-to-Treat lung cancer
NCT ID NCT04885998
Summary
This early-stage study tested the safety and best dose of a two-drug combination (tarlatamab plus AMG 404) for adults with small cell lung cancer that had worsened after standard chemotherapy. The main goal was to see how well patients tolerated the drugs and to check for any serious side effects. Researchers also looked for early signs that the treatment might help control the cancer.
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Contacts and locations
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Locations
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Chung Shan Medical University Hospital
Taichung, 40201, Taiwan
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Huntsman Cancer Institute
Salt Lake City, Utah, 84112, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Medizinische Universitaet Innsbruck
Innsbruck, 6020, Austria
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National Cancer Center Hospital
Chuo-ku, Tokyo, 104-0045, Japan
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National Cancer Center Hospital East
Kashiwa-shi, Chiba, 277-8577, Japan
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National Cancer Centre Singapore
Singapore, 169610, Singapore
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National University Hospital
Singapore, 119074, Singapore
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Northwestern University, Robert H Lurie Comprehensive Cancer Center
Chicago, Illinois, 60611, United States
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Taipei Veterans General Hospital
Taipei, 11217, Taiwan
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Tennessee Oncology, PLLC
Nashville, Tennessee, 37203, United States
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Universitaetsklinikum Allgemeines Krankenhaus Wien
Vienna, 1090, Austria
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Universitair Ziekenhuis Antwerpen
Edegem, 2650, Belgium
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Universitair Ziekenhuis Leuven - Campus Gasthuisberg
Leuven, 3000, Belgium
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University of Kentucky
Lexington, Kentucky, 40536, United States
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Wake Forest Baptist Comprehensive Cancer Research Center
Winston-Salem, North Carolina, 27157, United States
Conditions
Explore the condition pages connected to this study.