Scientists test new weapon combo against tough lung cancer

NCT ID NCT04686305

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This early-stage trial is testing the safety of combining a targeted drug (trastuzumab deruxtecan) with different immunotherapy drugs, with or without standard chemotherapy. It is for people with advanced non-small cell lung cancer that has a specific marker called HER2. The main goal is to find safe dose levels, while also checking if these combinations can help shrink tumors and control the cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Research Site
WITHDRAWN

Duarte, California, 91010, United States
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WITHDRAWN

Newport Beach, California, 92663, United States
Research Site
RECRUITING

Orange, California, 92868, United States
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WITHDRAWN

Santa Rosa, California, 95403, United States
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Westwood, Kansas, 66205, United States
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RECRUITING

Baltimore, Maryland, 21287, United States
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Detroit, Michigan, 48201, United States
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WITHDRAWN

Buffalo, New York, 14263, United States
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New York, New York, 10029, United States
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WITHDRAWN

The Bronx, New York, 10461, United States
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RECRUITING

Houston, Texas, 77030, United States
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RECRUITING

Fairfax, Virginia, 22031, United States
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WITHDRAWN

Tacoma, Washington, 98405, United States
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TERMINATED

Adelaide, 5000, Australia
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WITHDRAWN

Heidelberg, 3084, Australia
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RECRUITING

Nedlands, 6009, Australia
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COMPLETED

Edegem, 2650, Belgium
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NOT_YET_RECRUITING

Barretos, 14784-400, Brazil
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NOT_YET_RECRUITING

Porto Alegre, 90035-903, Brazil
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NOT_YET_RECRUITING

São Paulo, 05652-900, Brazil
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WITHDRAWN

Winnipeg, Manitoba, R3E 0V9, Canada
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WITHDRAWN

London, Ontario, N6A 5W9, Canada
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RECRUITING

Montreal, Quebec, H3T 1E2, Canada
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NOT_YET_RECRUITING

Fuzhou, 350011, China
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WITHDRAWN

Bordeaux, 33075, France
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RECRUITING

Dijon, 21079, France
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RECRUITING

Pierre-Bénite, 69495, France
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RECRUITING

Saint-Herblain, 44800, France
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RECRUITING

Villejuif, 94805, France
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RECRUITING

Kfar Saba, 4428164, Israel
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RECRUITING

Tel Litwinsky, 52620, Israel
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COMPLETED

Milan, 20133, Italy
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RECRUITING

Milan, 20162, Italy
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RECRUITING

Monza, 20052, Italy
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Naples, 80131, Italy
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RECRUITING

Padua, 35128, Italy
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RECRUITING

George Town, 10450, Malaysia
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Kuala Lumpur, 59100, Malaysia
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RECRUITING

Kuala Selangor, 62250, Malaysia
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RECRUITING

Kuching, 93586, Malaysia
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COMPLETED

Amsterdam, 1066 CX, Netherlands
Research Site
RECRUITING

Bacolod, 6100, Philippines
Research Site
WITHDRAWN

Cebu City, 6000, Philippines
Research Site
WITHDRAWN

City of Taguig, 1634, Philippines
Research Site
TERMINATED

Davao City, PH-8000, Philippines
Research Site
TERMINATED

Manila, 1000, Philippines
Research Site
WITHDRAWN

Manila, 1015, Philippines
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RECRUITING

Quezon City, 1100, Philippines
Research Site
RECRUITING

Quezon City, 1112, Philippines
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TERMINATED

San Juan City, 1500, Philippines
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RECRUITING

Gdansk, 80-214, Poland
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RECRUITING

Krakow, 30-727, Poland
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RECRUITING

Olsztyn, 10-357, Poland
Research Site
TERMINATED

Tomaszów Mazowiecki, 97-200, Poland
Research Site
RECRUITING

Warsaw, 02-781, Poland
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COMPLETED

Singapore, 119228, Singapore
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COMPLETED

Singapore, 168583, Singapore
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COMPLETED

Singapore, 308433, Singapore
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RECRUITING

Cheongju-si, 28644, South Korea
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RECRUITING

Goyang-si, 10408, South Korea
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RECRUITING

Jinju, 52727, South Korea
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RECRUITING

Seoul, 03722, South Korea
Research Site
WITHDRAWN

Seoul, 05505, South Korea
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RECRUITING

Seoul, 06351, South Korea
Research Site
WITHDRAWN

Badalona, 08013, Spain
Research Site
WITHDRAWN

Madrid, 28041, Spain
Research Site
WITHDRAWN

Seville, 41013, Spain
Research Site
WITHDRAWN

Valencia, 46010, Spain
Research Site
RECRUITING

Kaohsiung City, 833, Taiwan
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RECRUITING

Taichung, 402, Taiwan
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RECRUITING

Taichung, 40705, Taiwan
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RECRUITING

Tainan, 70403, Taiwan
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RECRUITING

Taipei, 100, Taiwan
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RECRUITING

Taipei, 11217, Taiwan
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RECRUITING

Taipei, 235, Taiwan
Research Site
RECRUITING

Taoyuan District, 333, Taiwan
Research Site
RECRUITING

Bangkok, 10300, Thailand
Research Site
RECRUITING

Bangkok, 10330, Thailand
Research Site
COMPLETED

Hat Yai, 90110, Thailand
Research Site
RECRUITING

Khon Kaen, 40002, Thailand
Research Site
NOT_YET_RECRUITING

Muang, 22000, Thailand
Research Site
RECRUITING

Muang, 50200, Thailand
Research Site
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Research Site
RECRUITING

Ankara, 6200, Turkey (Türkiye)
Research Site
RECRUITING

Bornova-Izmir, 35100, Turkey (Türkiye)
Research Site
NOT_YET_RECRUITING

Istanbul, 31755, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.

LOCALLY ADVANCED OR METASTATIC NON-SMALL CELL LUNG CANCER