First test of new drug combo for advanced lung cancer

NCT ID NCT03810807

Summary

This early-stage study tested whether combining two targeted cancer drugs (dacomitinib and osimertinib) is safe for people with advanced lung cancer that has spread and has a specific genetic change (EGFR mutation). The trial involved 22 patients who hadn't previously received this type of targeted treatment. Researchers aimed to find the highest dose patients could tolerate without severe side effects while checking if the combination showed any signs of helping shrink tumors.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.