New Two-Drug combo takes on standard chemo in major lung cancer trial

NCT ID NCT02542293

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large, late-stage trial is comparing a new two-drug immunotherapy combination (durvalumab + tremelimumab) against standard chemotherapy for people with advanced non-small cell lung cancer. The goal is to see if the combination helps patients live longer. The study enrolled nearly 1,000 adults who had not received prior treatment for their advanced cancer.

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Contacts and locations

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Locations

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Anaheim, California, 92801, United States
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San Diego, California, 92123, United States
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Santa Rosa, California, 95403, United States
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Louisville, Kentucky, 40202, United States
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Florham Park, New Jersey, 07932, United States
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Albuquerque, New Mexico, 87102, United States
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East Setauket, New York, 11733, United States
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Fresh Meadows, New York, 11366, United States
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Poughkeepsie, New York, 12601, United States
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Stony Brook, New York, 11794, United States
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Canton, Ohio, 44710, United States
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Columbus, Ohio, 43219, United States
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Zanesville, Ohio, 43701, United States
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Pittsburgh, Pennsylvania, 15212, United States
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Houston, Texas, 77090, United States
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Berazategui, B1884BBF, Argentina
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CABA, C1426ANZ, Argentina
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Ciudad de Buenos Aires, C1025ABI, Argentina
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Córdoba, 5000, Argentina
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La Rioja, 5300, Argentina
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Rosario, S2000KZE, Argentina
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San Salvador de Jujuy, 4600, Argentina
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Santa Rosa, 6300, Argentina
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Barretos, 14784-400, Brazil
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Belo Horizonte, 30110-022, Brazil
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Belo Horizonte, 30380-472, Brazil
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Fortaleza, 60336-045, Brazil
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Ijuí, 98700-000, Brazil
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Itajaí, 88301-220, Brazil
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Porto Alegre, 90035-003, Brazil
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Porto Alegre, 90160-093, Brazil
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Porto Alegre, 91350-200, Brazil
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São José do Rio Preto, 15090-000, Brazil
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São Paulo, 01221-020, Brazil
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São Paulo, 01246-000, Brazil
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São Paulo, 01323 900, Brazil
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São Paulo, 03102-002, Brazil
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Plovdiv, 4004, Bulgaria
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Shumen, 9700, Bulgaria
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Sofia, 1303, Bulgaria
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Sofia, 1330, Bulgaria
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Sofia, 1431, Bulgaria
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Sofia, 1784, Bulgaria
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Varna, 9010, Bulgaria
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Vratsa, 3000, Bulgaria
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Santiago, 7500713, Chile
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Santiago, 7500921, Chile
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Santiago, 7520349, Chile
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Santiago, 8380456, Chile
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Santiago, 8420383, Chile
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Temuco, 4810297, Chile
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Viña del Mar, 2520612, Chile
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Beijing, 100142, China
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Changchun, 130000, China
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Chongqing, 400030, China
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Guangzhou, 510100, China
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Hangzhou, 310022, China
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Shanghai, 200030, China
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Shanghai, 200032, China
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Ürümqi, 830000, China
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Wuhan, 430022, China
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Wuhan, 430030, China
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Odense C, 5000, Denmark
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Oulu, FI-90029, Finland
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Tampere, FI-33521, Finland
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Athens, 115 22, Greece
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Athens, 11527, Greece
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Athens, 14564, Greece
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Heraklion, 71110, Greece
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Holargos, Athens, 155 62, Greece
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Ioannina, 45000, Greece
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Hong Kong, Hong Kong
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King's Park, 150001, Hong Kong
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Shatin, 00000, Hong Kong
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Ahmedabad, 380016, India
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Bangalore, 560068, India
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Bangalore, 560076, India
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Chennai, 600035, India
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Gūrgaon, 122001, India
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Karamsad, 388325, India
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New Delhi, 110 085, India
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Beersheba, 8410101, Israel
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Jerusalem, 91031, Israel
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Kfar Saba, 95847, Israel
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Nahariya, 22100, Israel
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Petah Tikva, 49100, Israel
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Ramat Gan, 5265601, Israel
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Bunkyō City, 160-0023, Japan
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Fukushima, 960-1295, Japan
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Habikino-shi, 583-8588, Japan
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Hirosaki-shi, 036-8545, Japan
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Iizuka-shi, 820-8505, Japan
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Iwakuni-shi, 740-8510, Japan
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Kanazawa, 920-8641, Japan
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Kishiwada-shi, 596-8501, Japan
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Kobe, 650-0047, Japan
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Kurume-shi, 830-0011, Japan
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Kyoto, 607-8062, Japan
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Mitaka-shi, 181-8611, Japan
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Nagaoka-shi, 940-2085, Japan
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Nagoya, 460-0001, Japan
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Nagoya, 466-8560, Japan
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Niigata, 951-8566, Japan
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Okayama, 700-8607, Japan
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Osaka, 541-8567, Japan
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Saga, 840-8571, Japan
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Sagamihara-shi, 252-0375, Japan
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Sakaishi, 591-8555, Japan
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Sendai, 980-0873, Japan
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Tokushima, 770-8503, Japan
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Ube-shi, 755-0241, Japan
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Wakayama, 641-8510, Japan
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Yokohama, 236-0004, Japan
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Yokohama, 241-8515, Japan
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Kuala Lumpur, 59100, Malaysia
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Kuantan, 25100, Malaysia
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Kuching, 93586, Malaysia
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Acapulco, 39670, Mexico
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Aguascalientes, 20020, Mexico
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Mérida, 97134, Mexico
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México, 06100, Mexico
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México, 14080, Mexico
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Monterrey, 64710, Mexico
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Arequipa, AREQUIPA01, Peru
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Bellavista, CALLAO 2, Peru
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Lima, 15033, Peru
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Lima, 41, Peru
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Lima, L27, Peru
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Lima, LIMA 34, Peru
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Lima, LIMA 41, Peru
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Baguio City, 2600, Philippines
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Cebu, 6000, Philippines
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Las Piñas, PH-1704, Philippines
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Manila, 1000, Philippines
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Manila, 1003, Philippines
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Quezon City, 1112, Philippines
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Bydgoszcz, 85-796, Poland
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Kielce, 25-734, Poland
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Krakow, 31-202, Poland
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Lodz, 93-513, Poland
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Mrozy, 05-320, Poland
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Olsztyn, 10-357, Poland
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Poznan, 60-569, Poland
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Warsaw, 01-138, Poland
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Warsaw, 02-781, Poland
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Wodzisław Śląski, 44-300, Poland
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Amadora, 2720-276, Portugal
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Lisbon, 1500-650, Portugal
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Porto, 4099-001, Portugal
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Porto, 4100-180, Portugal
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Porto, 4200-319, Portugal
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Doha, P.O. Box 3050, Qatar
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Suceava, 720237, Romania
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Moscow, 105229, Russia
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Moscow, 115280, Russia
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Moscow, 125367, Russia
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Omsk, 644013, Russia
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Saint Petersburg, 194291, Russia
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Saint Petersburg, 197022, Russia
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Saint Petersburg, 197183, Russia
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Saint Petersburg, 197342, Russia
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Saint Petersburg, 197758, Russia
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Dammam, 31444, Saudi Arabia
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Riyadh, 11426, Saudi Arabia
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Riyadh, 12372, Saudi Arabia
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Singapore, 119228, Singapore
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Singapore, 217562, Singapore
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Singapore, 258499, Singapore
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Singapore, 308433, Singapore
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Daegu, 41404, South Korea
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Hwasun-gun, 58128, South Korea
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Seoul, 05030, South Korea
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Seoul, 06273, South Korea
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Seoul, 08308, South Korea
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Eskilstuna, 63188, Sweden
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Linköping, 581 85, Sweden
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Stockholm, 171 64, Sweden
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Uppsala, 751 85, Sweden
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Adana, 01120, Turkey (Türkiye)
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Ankara, 06200, Turkey (Türkiye)
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Ankara, 06230, Turkey (Türkiye)
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Ankara, 06280, Turkey (Türkiye)
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Ankara, 6500, Turkey (Türkiye)
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Istanbul, 31755, Turkey (Türkiye)
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Istanbul, 34030, Turkey (Türkiye)
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Istanbul, 34349, Turkey (Türkiye)
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Izmir, 35100, Turkey (Türkiye)
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Chernivtsі, 58013, Ukraine
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Dnipro, 49102, Ukraine
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Ivano-Frankivsk, 76018, Ukraine
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Kapitanivka Village, 08111, Ukraine
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Kharkiv Region, 61070, Ukraine
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Kirovohrad, 25006, Ukraine
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Kyiv, 03115, Ukraine
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Kyiv, 04107, Ukraine
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Liutizh, 07352, Ukraine
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Lviv, 79031, Ukraine
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Odesa, 65055, Ukraine
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Sumy, 40022, Ukraine
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Uzhhorod, 88000, Ukraine
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Vinnytsia, 21029, Ukraine
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Guildford, United Kingdom
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London, EC1M 6BQ, United Kingdom
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London, NW1 2PG, United Kingdom
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London, W6 8RF, United Kingdom
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Manchester, M20 4BX, United Kingdom
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Metropolitan Borough of Wirral, CH63 4JY, United Kingdom
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Nottingham, NG5 1PB, United Kingdom
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Taunton, TA1 5DA, United Kingdom
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Wolverhampton, WV10 0QP, United Kingdom

Conditions

Explore the condition pages connected to this study.

NON SMALL CELL LUNG CARCINOMA NSCLC