New hope for lung cancer patients who stopped responding to standard treatment

NCT ID NCT00596648

Summary

This study tested whether adding a new drug called cabozantinib to an existing lung cancer drug (erlotinib) could help patients whose cancer had started growing again after initially responding to erlotinib alone. The trial involved 92 adults with advanced non-small cell lung cancer. Researchers first determined safe doses of the drug combination, then measured how well it worked at shrinking tumors compared to cabozantinib alone.

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Contacts and locations

Locations

  • Case Western Reserve University

    Cleveland, Ohio, 44106, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Georgetown University/Lombardi Comprehensive Cancer Center

    Washington D.C., District of Columbia, 20007, United States

  • Katmai Oncology Group

    Anchorage, Alaska, 99508, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Park Nicollet Institute

    Saint Louis Park, Minnesota, 55416, United States

  • Stanford University Medical Center

    Palo Alto, California, 94305, United States

  • Summit Medical Group

    Berkeley Heights, New Jersey, 07922, United States

  • Swedish Cancer Institute

    Seattle, Washington, 98104, United States

  • University of California, Davis

    Sacramento, California, 95817, United States

  • University of Chicago Medical Center

    Chicago, Illinois, 60637, United States

  • University of Washington/ Seattle Cancer Care Alliance

    Seattle, Washington, 98109, United States

  • Yale University School of Medicine

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.