Could a lung wash replace needle biopsies for cancer gene tests?

NCT ID NCT07188480

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study explores whether genetic material from tiny particles called extracellular vesicles, collected during a bronchial lavage (a lung wash), can be used for advanced genetic testing in people with advanced lung cancer. The goal is to see if this less invasive method can provide the same genetic information as traditional tissue biopsies. If it works, it could reduce the need for repeated, risky biopsies to guide treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bronchial lavage for NGS analysis

What this could lead to

If successful, this could offer a less invasive way to get genetic information from lung tumors, helping doctors choose targeted therapies without repeated biopsies.

What could go wrong

This is a very small, early feasibility study with only 10 participants. It may not work in all patients, and the method needs to be validated against standard biopsy results.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NON-SMALL CELL LUNG CANCER (NSCLC) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna

    RECRUITING

    Bologna, Bologna, 40138, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••