New drug duo targets lung cancer in the brain after other treatments fail

NCT ID NCT04965090

Summary

This study tested whether two drugs, amivantamab and lazertinib, could help control advanced lung cancer that has an EGFR mutation and has spread to the brain or spinal fluid. It was for patients whose cancer had gotten worse or spread to the central nervous system despite previous standard treatments. The main goal was to see how well the drug combination shrank these brain and spinal fluid tumors.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.