Can a flash of light beat a blinding eye infection?
NCT ID NCT07743489
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This study tests whether a light-activated treatment called Rose Bengal photodynamic therapy can help people with a severe fungal eye infection called Fusarium keratitis. The infection can cause vision loss, and standard treatments may not always work. Participants receive either the active light therapy or a sham procedure, and their vision is checked after three months. The goal is to see if this approach can clear the infection and improve visual outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Rose Bengal photodynamic therapy (RB-PDT), a light-activated treatment applied to the cornea
- What this could lead to
- If effective, this could offer a new way to treat Fusarium keratitis, potentially saving vision and reducing the need for more invasive procedures.
- What could go wrong
- The trial is still in progress, and results may not confirm benefit. Risks include possible discomfort, corneal damage, or lack of improvement over standard care.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Aravind Eye Care System
Madurai, Tamil Nadu, 625 020, India
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Federal University of São Paulo
São Paulo, 04023-062, Brazil
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Stanford University
Palo Alto, California, 94303, United States
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University of Miami - Bascom Palmer Eye Institute
Miami, Florida, 33136, United States