New drug trial aims to put the brakes on devastating brain disease
NCT ID NCT05104476
Summary
This study is testing an investigational drug called Lu AF82422 to see if it can slow down the progression of multiple system atrophy (MSA), a rare and serious brain disorder. About 64 participants with MSA will receive either the drug or a placebo for nearly a year to compare their symptoms and daily function. The main goal is to see if the drug can help patients maintain their abilities longer by slowing the worsening of the disease.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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CenExel Rocky Mountain Clinical Research, LLC
Englewood, Colorado, 80113, United States
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Columbia University Medical Center - The Neurological Institute of New York
New York, New York, 10032, United States
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Endeavor Health - Glenbrook Hospital
Glenview, Illinois, 60026, United States
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Fujita Health University Hospital
Toyoake, Aichi-ken, 470-1192, Japan
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Gifu University Hospital
Gifu, Gifu, 501-1194, Japan
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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NYU Langone Health Medical Center
New York, New York, 10016, United States
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National Hospital Organization Sendai Nishitaga Hospital
Sendai, Miyagi, 982-8555, Japan
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Parkinson's Disease And Movement Disorder Center Of Boca Raton
Boca Raton, Florida, 33486, United States
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Penn State Milton S. Hershey Medical Center - Penn State Hershey Neuroscience Institute (PSHNI)
Hershey, Pennsylvania, 17033, United States
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Rush University Medical Center, Rush University Cancer Center
Chicago, Illinois, 60612, United States
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The Parkinsons and Movement Disorder Institute
Fountain Valley, California, 92708, United States
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University Nebraska Medical Center
Omaha, Nebraska, 68198-8440, United States
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University Of Pittsburgh
Pittsburgh, Pennsylvania, 15213, United States
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University of California - San Diego
La Jolla, California, 92037, United States
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University of California, San Francisco Neurosciences Clinical Research Unit
San Francisco, California, 94158, United States
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University of Florida Norman Fixel Institute for Neurological Diseases
Gainesville, Florida, 32608, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19107, United States
Conditions
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