New radioactive therapy targets mysterious cancers

NCT ID NCT07434180

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests a new radioactive drug, Lu-177 FAP-2286, in 20 patients with cancer of unknown primary (CUP). The drug targets a protein found on cells near tumors, delivering radiation directly to the cancer. The main goal is to see if the treatment can shrink tumors or stop them from growing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lu-177 FAP-2286 (a radioactive drug that targets cancer cells)

What this could lead to

If successful, this could offer a new treatment option for patients with cancer of unknown primary, potentially shrinking tumors and delaying disease progression.

What could go wrong

This is a small, early-phase trial with only 20 participants, so results may not apply to everyone. The treatment involves radiation, which can cause side effects, and it is not yet known if it will be effective.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer of unknown primary site

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••