Blood test could unlock new treatments for mysterious cancer

NCT ID NCT06695494

Recruiting now Knowledge-focused Sponsor: The Christie NHS Foundation Trust Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

Cancer of Unknown Primary (CUP) is a rare cancer where doctors cannot find where it started, and it is often deadly within months. This study will test a blood-based genomic test in 100 people with CUP to see if it can find genetic changes that point to new treatment options. The goal is to improve understanding of CUP and help patients access personalized therapies or clinical trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Blood sample collection for gene panel testing
What this could lead to: If successful, this could help doctors identify more treatment options for people with Cancer of Unknown Primary using a simple blood test.
What could go wrong: This is an early-stage study with only 100 participants, so results may not apply to everyone. The blood test may not always provide useful information.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer of unknown primary site neoplasm Neoplasms, Unknown Primary

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER OF UNKNOWN PRIMARY NEOPLASM, UNKNOWN PRIMARY

Contacts and locations

Locations

Blackpool Teaching Hospitals NHS Foundation Trust
RECRUITING

Blackpool, United Kingdom
Lancashire Teaching Hospitals NHS Foundation Trust
RECRUITING

Preston, United Kingdom
Northern Care Alliance NHS Foundation Trust
RECRUITING

Manchester, United Kingdom
The Christie NHS Foundation Trust
RECRUITING

Manchester, Greater Manchester, M20 4BX, United Kingdom
The Clatterbridge Cancer Centre NHS Foundation Trust
RECRUITING

Liverpool, Merseyside, United Kingdom
University Hospitals of Morecambe Bay NHS Trust
RECRUITING

Morecambe, United Kingdom

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