New hope for PNH: experimental drug LP-005 enters Mid-Stage trial

NCT ID NCT07212426

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests an experimental drug called LP-005 in 30 adults with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disorder that destroys red blood cells. The goal is to see if LP-005 can lower a key disease marker (LDH) and raise hemoglobin levels without needing blood transfusions. Participants receive LP-005 injections and are monitored for safety and effectiveness over the study period.

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Conditions

The condition(s) this trial relates to.

Hemoglobinuria, Paroxysmal paroxysmal nocturnal hemoglobinuria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of Nanjing Medical University

    Nanjing, China