Cancer trial seeks same results with fewer side effects

NCT ID NCT01896479

Summary

This study aims to see if a lower daily dose (60 mg) of the cancer drug cabozantinib works as well as the standard higher dose (140 mg) for people with advanced medullary thyroid cancer that is getting worse. Researchers want to find out if the lower dose can control the cancer for a similar length of time while causing fewer side effects. The trial involves about 250 participants and compares the two doses directly.

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Contacts and locations

Locations

  • Study site

    St Leonards, New South Wales, 2065, Australia

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    Herston, Queensland, 4006, Australia

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    Kurralta Park, South Australia, 5037, Australia

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    Parkville, Victoria, 3050, Australia

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    Québec, Quebec, JIH 5N4, Canada

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    Toronto, M5G 2M9, Canada

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    Osijek, 31000, Croatia

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    Zagreb, 10000, Croatia

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    Zagreb, 1000, Croatia

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    Bordeaux, Gironde, 33076, France

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    Angers, Maine-et-Loire, 49933, France

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    Lyon, Rhône, 69373, France

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    Villejuif, Val-de-Marne, 94805, France

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    Dijon, 21079, France

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    Paris, 75013, France

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    Strasbourg, 67065, France

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    Budapest, 1088, Hungary

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    Debrecen, 4032, Hungary

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    Jerusalem, 91120, Israel

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    Petah Tikva, 49100, Israel

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    Safed, 13100, Israel

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    Catania, CT, 95124, Italy

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    Roma, RM, 00161, Italy

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    Siena, SI, 53100, Italy

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    Pisa, Tuscany, 56124, Italy

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    Milan, 20133, Italy

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    Padua, 35138, Italy

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    Torino, 10153, Italy

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    Amsterdam, North Holland, 1066 CX, Netherlands

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    Leiden, South Holland, 2333 ZA, Netherlands

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    Groningen, 9713 GZ, Netherlands

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    Poznan, Greater Poland Voivodeship, 60-355, Poland

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    Gliwice, Silesian Voivodeship, 44-100, Poland

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    Bucharest, 10825, Romania

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    Bucharest, 11863, Romania

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    Cluj-Napoca, 400058, Romania

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    Timișoara, 300723, Romania

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    Novosibirsk, 630068, Russia

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    Obninsk, 249036, Russia

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    Saint Petersburg, 197089, Russia

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    Yaroslavl, 150040, Russia

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    Goyang, Gyeonggido, 410769, South Korea

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    Seoul, 110744, South Korea

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    Seoul, 135-710, South Korea

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    Barcelona, 08035, Spain

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    Madrid, 28034, Spain

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    Madrid, 28046, Spain

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    Lund, Skane Ian, SE-22185, Sweden

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    Uppsala, Uppsala Ian, 75185, Sweden

Conditions

Explore the condition pages connected to this study.