Could a lower drug dose be safer and just as effective for kids with rare tumor?
NCT ID NCT07656909
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two doses of sirolimus (low vs high) given with prednisolone to children aged 0-18 who have a rare blood vessel tumor called kaposiform hemangioendothelioma with a serious blood clotting problem (Kasabach-Merritt phenomenon). The goal is to see if the lower dose works just as well to restore platelet counts but causes fewer side effects. About 76 children will take part and be monitored with blood tests and imaging.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
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The condition terms exactly as the trial's registrant entered them.
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Email: •••••@•••••
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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West China Hospital of Sichuan University
RECRUITINGChengdu, Sichuan, 610041, China
Contact Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••