Blood cancer drug shows promise in Long-Term study

NCT ID NCT06752941

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 36 Italian patients with Polycythemia Vera who responded well to Ropeginterferon alfa-2b in an earlier trial. Researchers will check every 6 months whether the treatment continues to keep their red blood cell levels normal and prevent the disease from getting worse. The goal is to see if long-term use of this drug can maintain control of the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ropeginterferon alfa-2b

What this could lead to

If successful, this study could show that long-term use of Ropeginterferon alfa-2b helps keep Polycythemia Vera under control without disease progression.

What could go wrong

This is an observational study with no control group, so it cannot prove cause and effect. Results may not apply to all patients, and long-term side effects are still possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acquired polycythemia vera

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • A.O.U. Città della Salute e della Scienza di Torino - Ospedale Molinette- S.C. Ematologia U

    RECRUITING

    Torino, 10126, Italy

    Contact Email: •••••@•••••

    Contact

  • ASST Papa Giovanni XXIII, SC Ematologia

    RECRUITING

    Bergamo, Italy

    Contact

    Contact

    Contact

    Contact Email: •••••@•••••

    Contact

  • ASST Sette Laghi, Ospedale di Circolo e F. Macchi, Divisione UO Ematologia

    RECRUITING

    Varese, Italy

    Contact

    Contact Email: •••••@•••••

  • Azienda Ospedaliera Universitaria Federico II di Napoli Divisione di Ematologia e Trapianti del Midollo

    RECRUITING

    Naples, 80131, Italy

    Contact Email: •••••@•••••

    Contact

    Contact

    Contact

  • Azienda Ospedaliero Universitaria Careggi, SOD Ematologia

    RECRUITING

    Florence, Italy

    Contact

    Contact Email: •••••@•••••

    Contact

  • Azienda Ospedaliero Universitaria Maggiore della Carità di Novara SCDU Ematologia

    RECRUITING

    Novara, 28100, Italy

    Contact

    Contact Email: •••••@•••••

  • Azienda ULSS 8 Berica - Ospedale San Bortolo, Divisione di Ematologia

    NOT_YET_RECRUITING

    Vicenza, Italy

    Contact Email: •••••@•••••

    Contact

  • Fondazione IRCCS Cà Granda - Ospedale Maggiore Policlinico, SC Ematologia

    RECRUITING

    Milan, Italy

    Contact

    Contact Email: •••••@•••••

  • Fondazione IRCCS Policlinico San Matteo, Divisione Ematologia

    NOT_YET_RECRUITING

    Pavia, Lombardy, 27100, Italy

    Contact Email: •••••@•••••

    Contact

  • Ospedale Borgo Roma, Divisione Ematologia

    NOT_YET_RECRUITING

    Verona, Veneto, 37134, Italy

    Contact Email: •••••@•••••

    Contact

    Contact

  • Ospedale San Raffaele, Unità Operativa di Ematologia e Trapianto Midollo Osseo

    RECRUITING

    Milan, Italy

    Contact Email: •••••@•••••

    Contact

  • Policlinico S. Orsola - Malpighi, UO Ematologia

    RECRUITING

    Bologna, Italy

    Contact

    Contact

    Contact Email: •••••@•••••

  • Policlinico Universitario Fondazione Agostino Gemelli

    NOT_YET_RECRUITING

    Roma, 00168, Italy

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

    Contact

    Contact