Blood cancer drug shows promise in Long-Term study

NCT ID NCT06752941

Completed Disease control Sponsor: FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This study follows 36 Italian patients with Polycythemia Vera who responded well to Ropeginterferon alfa-2b in an earlier trial. Researchers will check every 6 months whether the treatment continues to keep their red blood cell levels normal and prevent the disease from getting worse. The goal is to see if long-term use of this drug can maintain control of the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ropeginterferon alfa-2b
What this could lead to: If successful, this study could show that long-term use of Ropeginterferon alfa-2b helps keep Polycythemia Vera under control without disease progression.
What could go wrong: This is an observational study with no control group, so it cannot prove cause and effect. Results may not apply to all patients, and long-term side effects are still possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acquired polycythemia vera

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POLYCYTHEMIA VERA

Contacts and locations

Locations

A.O.U. Città della Salute e della Scienza di Torino - Ospedale Molinette- S.C. Ematologia U

Torino, 10126, Italy
ASST Papa Giovanni XXIII, SC Ematologia

Bergamo, Italy
ASST Sette Laghi, Ospedale di Circolo e F. Macchi, Divisione UO Ematologia

Varese, Italy
Azienda Ospedaliera Universitaria Federico II di Napoli Divisione di Ematologia e Trapianti del Midollo

Naples, 80131, Italy
Azienda Ospedaliero Universitaria Careggi, SOD Ematologia

Florence, Italy
Azienda Ospedaliero Universitaria Maggiore della Carità di Novara SCDU Ematologia

Novara, 28100, Italy
Azienda ULSS 8 Berica - Ospedale San Bortolo, Divisione di Ematologia

Vicenza, Italy
Fondazione IRCCS Cà Granda - Ospedale Maggiore Policlinico, SC Ematologia

Milan, Italy
Fondazione IRCCS Policlinico San Matteo, Divisione Ematologia

Pavia, Lombardy, 27100, Italy
Ospedale Borgo Roma, Divisione Ematologia

Verona, Veneto, 37134, Italy
Ospedale San Raffaele, Unità Operativa di Ematologia e Trapianto Midollo Osseo

Milan, Italy
Policlinico S. Orsola - Malpighi, UO Ematologia

Bologna, Italy
Policlinico Universitario Fondazione Agostino Gemelli

Roma, 00168, Italy

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