Warm gas during keyhole surgery may cut pain and opioid use

NCT ID NCT05934981

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether using warm, humidified carbon dioxide gas during low-pressure laparoscopic colorectal surgery reduces pain 24 hours after the procedure. 148 adults having surgery for colon or rectal tumors (benign or malignant) took part. One group received warm, moist gas; the other received standard cold, dry gas. The main goal was to see how many patients had mild pain (score 3 or less on a 0–10 scale) without needing strong painkillers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

warm, humidified carbon dioxide gas used during laparoscopic surgery

What this could lead to

If it works, this could lead to less pain and fewer opioids after colorectal surgery, helping patients recover more comfortably.

What could go wrong

This is a small, completed trial with 148 patients. The benefit may be small or not apply to all surgeries. Pain is subjective and results may not be widely generalizable.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colonic neoplasm colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinique TIVOLI DUCOS - Bordeaux Colorectal Institute

    Bordeaux, France

  • HOPITAL NORD APHM - Service de Chirurgie Digestive

    Marseille, France