Diet change may soothe stubborn heartburn when pills fail

NCT ID NCT02471989

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a low-FODMAP diet could help people with gastro-esophageal reflux disease (GERD) whose symptoms persist despite taking standard acid-reducing drugs (PPIs). Thirty-one adults with confirmed reflux were randomly assigned to either a low-FODMAP diet or a standard GERD diet for several weeks. The main goal was to see if the low-FODMAP diet led to more people achieving symptom remission, measured by a reflux symptom questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Low-FODMAP diet
What this could lead to
If it works, this could offer a dietary approach to ease reflux symptoms for people whose GERD doesn't respond to standard acid-reducing medications.
What could go wrong
This was a small, early study with only 31 participants. Dietary changes can be hard to maintain, and results may not apply to everyone with GERD.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Explorations fonctionnelles

    Lyon, 69437, France

  • Explorations fonctionnelles Digestives

    Rennes, 35033, France

  • Gastroentérologie

    Colombes, 92700, France

  • Gastroentérologie

    Nantes, 44093, France

  • Gastroentérologie

    Rouen, 76031, France

  • Hépato-Gastroentérologie et oncologie digestive,

    Bordeaux, 33075, France