Could a Low-Dose steroid tame Immunotherapy's liver side effect?

NCT ID NCT07167251

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 22 times

Summary

This study looks at whether a low dose of the steroid prednisolone can effectively treat liver inflammation (hepatitis) caused by immune checkpoint inhibitors in cancer patients. About 63 adults with grade 2-3 liver inflammation will receive 0.5-1 mg per kg of prednisolone. The goal is to see if this approach resolves the inflammation within 8 weeks without needing higher doses or additional drugs.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Royal Marsden Hospital

    NOT_YET_RECRUITING

    London, SW3 6JJ, United Kingdom

  • University Hospital Basel

    RECRUITING

    Basel, Canton of Basel-City, 4031, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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