Low-Dose radiation plus immunotherapy shows promise in rectal cancer trial
NCT ID NCT07448142
First seen Apr 18, 2026 · Last updated May 01, 2026 · Updated 1 time
Summary
This study tests whether a low dose of radiation, combined with an immunotherapy drug (pucotenlimab) and chemotherapy (CAPEOX), can shrink or eliminate locally advanced rectal cancer before surgery. About 50 adults with a specific type of rectal cancer (pMMR/MSS) will receive either 2 Gy or 5 Gy of radiation, followed by the drug combination. The goal is to see if this approach leads to a complete response, meaning no cancer is detectable after treatment.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dept. of Colorectal Surgery, Sun Yat-sen University Cancer Center. Yuexiu District, Dongfeng East Road 651
RECRUITINGGuangzhou, Guanggong, 510060, China
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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