Lower drug dose may prevent transplant complications without extra risk

NCT ID NCT07319000

First seen Jan 09, 2026 · Last updated May 12, 2026 · Updated 20 times

Summary

This study tested whether a lower dose of a drug called cyclophosphamide could prevent graft-versus-host disease (GVHD) in 35 adults receiving stem cell transplants for blood cancers or disorders. GVHD is a serious side effect where donor cells attack the patient's body. The lower dose aimed to be as effective as the standard dose while helping blood cells recover faster. The study found that the low dose kept severe GVHD rates low, similar to historical results.

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Contacts and locations

Locations

  • Hospital Universitario de Monterrey

    Monterrey, 64460, Mexico

Conditions

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