Can a safer opioid replace oxycodone? new study investigates low-dose buprenorphine
NCT ID NCT05988710
First seen Jan 12, 2026 · Last updated Apr 29, 2026 · Updated 14 times
Summary
This study aims to see if low-dose buprenorphine, a partial opioid, can provide similar pain relief to oxycodone but with less risk of abuse. Researchers will give 60 healthy adults different doses of buprenorphine, oxycodone, or a placebo, then measure pain response and drug liking. The goal is to find a safer alternative for pain management.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
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Locations
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37069, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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