Can a simple eye drop slow down worsening nearsightedness in kids?

NCT ID NCT07329777

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether low-dose atropine eye drops (0.025%) can safely slow the progression of myopia (nearsightedness) in children aged 5 to 10. Over two years, 144 children will receive either the active drops or a placebo. The goal is to see if the drops reduce how quickly their eyesight gets worse.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
low-dose atropine sulfate eye drops (0.025%)
What this could lead to
If it works, this could provide a safe, daily eye drop option to slow down worsening nearsightedness in children, reducing the need for stronger glasses later.
What could go wrong
This is a relatively small, early-phase trial (144 children) and the effect may be modest. Atropine can cause light sensitivity or blurry near vision, and long-term safety beyond 2 years is not yet known.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Pakar Kanak-Kanak UKM

    RECRUITING

    Kuala Lumpur, Cheras, 56000, Malaysia

  • Universiti Malaya Medical Centre

    RECRUITING

    Kuala Lumpur, Petaling Jaya, 50603, Malaysia

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