New Dual-Pacing strategy could boost heart function in failure patients

NCT ID NCT07664189

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether a new pacing method called LOT-CRT, which paces two areas of the heart at once, works better than standard pacing alone in people with heart failure. Ten patients will each receive a special pacemaker and try both pacing settings for 6 months each. Researchers will compare heart function, symptoms, and quality of life to see which approach is more effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cardiac resynchronization therapy pacemaker (CRT-P) with leads in the left bundle branch area and coronary sinus

What this could lead to

If successful, this could point toward a more effective pacing strategy to improve heart function and quality of life in heart failure patients.

What could go wrong

This is a very small pilot study with only 10 patients, so results may not apply to everyone. The crossover design is exploratory, and the approach may not show clear benefits over standard pacing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinica CardioVID

    Medellín, Antioquia, 050036, Colombia