New Dual-Pacing strategy could boost heart function in failure patients

NCT ID NCT07664189

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This pilot study tests whether a new pacing method called LOT-CRT, which paces two areas of the heart at once, works better than standard pacing alone in people with heart failure. Ten patients will each receive a special pacemaker and try both pacing settings for 6 months each. Researchers will compare heart function, symptoms, and quality of life to see which approach is more effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cardiac resynchronization therapy pacemaker (CRT-P) with leads in the left bundle branch area and coronary sinus
What this could lead to
If successful, this could point toward a more effective pacing strategy to improve heart function and quality of life in heart failure patients.
What could go wrong
This is a very small pilot study with only 10 patients, so results may not apply to everyone. The crossover design is exploratory, and the approach may not show clear benefits over standard pacing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinica CardioVID

    Medellín, Antioquia, 050036, Colombia