Blood pressure drug may boost knee surgery recovery

NCT ID NCT06933706

Recruiting now Symptom relief Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking losartan for 30 days after multi-ligament knee surgery helps people regain motion, strength, and return to work or sport. About 90 adults with severe knee injuries will be randomly assigned to receive losartan or a placebo. The goal is to reduce inflammation and improve outcomes in the first year after surgery.

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Conditions

The condition(s) this trial relates to.

Knee Dislocation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTI-LIGAMENT KNEE INJURY

Contacts and locations

Locations

Mass General Brigham
RECRUITING

Foxborough, Massachusetts, 02035, United States
University of Kentucky
NOT_YET_RECRUITING

Lexington, Kentucky, 40536, United States
Walter Reed National Military Medical Center
NOT_YET_RECRUITING

Bethesda, Maryland, 20814, United States