3-Year safety check for Kids' lung scarring drug

NCT ID NCT05285982

Summary

This study tested the long-term safety of nintedanib, a medication that slows lung scarring, in children and adolescents with progressive interstitial lung disease. Participants aged 6-17 took nintedanib capsules twice daily for at least 3 years while researchers monitored for side effects. The goal was to understand if this adult-approved treatment is well-tolerated in younger patients over extended periods.

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Contacts and locations

Locations

  • Azienda Ospedaliera Meyer

    Florence, 50139, Italy

  • BC Children's Hospital

    Vancouver, British Columbia, V6H 3N1, Canada

  • Brussels - UNIV HUDERF

    Brussels, 1020, Belgium

  • Centro de Pesquisa Clinica do Instituto da Crianca - HCFMUSP

    São Paulo, 5403-900, Brazil

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15224, United States

  • Clinical Research Institute S.C.

    Tlalnepantla, 54055, Mexico

  • General Hospital of Thessaloniki "Ippokrateio"

    Thessaloniki, 54642, Greece

  • HOP Intercommunal

    Créteil, 94010, France

  • Hamburger Zentrum für Kinder- und Jugendrheumatologie

    Hamburg, 22081, Germany

  • Hospital Universitari Vall D Hebron

    Barcelona, 08035, Spain

  • Hospital Virgen del Rocío

    Seville, 41013, Spain

  • Hospital de Niños Dr. Ricardo Gutierrez

    CABA, C1425EFD, Argentina

  • Hospital de Pediatria Prof. Dr. Juan P. Garrahan

    CABA, C1245AAM, Argentina

  • Independent Public Teaching Children's Hospital

    Warsaw, 02091, Poland

  • King's College Hospital

    London, SE5 9RS, United Kingdom

  • Oslo Universitetssykehus HF, Rikshospitalet

    Oslo, N-0372, Norway

  • Osp. Pediatrico Bambin Gesù

    Roma, 00165, Italy

  • Serviços Medicos Respirar Sul Fluminense

    Barra Mansa, 27323240, Brazil

  • Tampere University Hospital

    Tampere, 33520, Finland

  • Teaching Hospital Motol, Oncology Clinic

    Prague, 150 06, Czechia

  • The Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada

  • ULS de Santa Maria, E.P.E

    Lisbon, 1649-035, Portugal

  • ULS de São José, E.P.E. - Hospital Dona Estefânia

    Lisbon, 1169-045, Portugal

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Weill Cornell Medicine-New York-60569

    New York, New York, 10021, United States

Conditions

Explore the condition pages connected to this study.